| Type | Description |
|---|---|
| Definition | cytidine monophospho-N-acetylneuraminic acid hydroxylase |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:16:00 | Human evolutionary loss of CMAH likely contributes to atherosclerosis predisposition via multiple intrinsic and extrinsic mechanisms. | 31332008 |
| 2017-12-30 12:41:00 | These findings have the potential to significantly advance our understanding of how this enigmatic tumor-associated antigen is produced in humans, and also suggest a possible mechanism of action of anti-tumor antibodies that recognize hypoxia markers, such as 14F7. | 29196263 |
| 2017-09-16 11:20:00 | this study shows that Cmah(-/-) mice manifest a decreased survival in endotoxemia following bacterial lipopolysaccharide injection, and that macrophages from Cmah(-/-) mice secrete more inflammatory cytokines with LPS stimulation and show more phagocytic activity | 28148732 |
| 2016-09-03 10:58:00 | Used CMP-Neu5Ac Hydroxylase null mouse models to study the modification/turnover of gene products that are altered in humans due to evolutionary loss of Neu5Gc. | 26558285 |
| 2016-05-21 11:53:00 | The target miRNAs are closely associated with dysregulation of insulin/PI3K-AKT signaling, suggesting that the Cmah-null mice could be a useful model for studying diabetes. | 25243123 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CMAH_MOUSE
UniprotKB:
Q61419
UniParc:
UPI000050AAD9,
UPI0000028630
EMBL:
BC055079,
AB061346,
D21826,
AB061276,
AB061277,
AL589744
Ensembl:
ENSMUSG00000016756
KO:
mmu:12763
|
| Nucleutide sequences |
EMBL-CDS:
AAH55079.1,
BAB91361.1,
BAB91362.1,
BAB91553.1,
BAA04850.1
Ensembl_TRS:
ENSMUST00000224657,
ENSMUST00000110391,
ENSMUST00000050859,
ENSMUST00000224953,
ENSMUST00000167746
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061045,
ENSMUSP00000153652,
ENSMUSP00000153495,
ENSMUSP00000129007,
ENSMUSP00000106021
RefSeq:
XP_011242568.1,
XP_011242567.1,
XP_036013735.1,
NP_001104580.1,
NP_001271449.1,
XP_011242576.1,
NP_001271448.1,
NP_031743.3
|
| Others |
UniRef100:
UniRef100_Q61419
UniRef90:
UniRef90_Q61419
UniRef50:
UniRef50_Q61419
UniGene:
Mm.8396
CCDS:
CCDS26376.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员