| Type | Description |
|---|---|
| Definition | tripeptidyl peptidase I |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 11:43:00 | telomeres are protected from hyper-resection through the repression of the ATM and ATR kinases by TRF2 and TPP1-bound POT1a/b, respectively. | 26778124 |
| 2015-02-07 11:47:00 | Rssults suggested that CLN2, CLN3 and CLN5 genes may play an important role in early embryonal neurogenesis. | 25303899 |
| 2015-01-24 11:49:00 | demonstrated that cells expressing TIN2DeltaTPP1 instead of wild-type TIN2 phenocopy the POT1a,b knockout setting without showing additional phenotypes | 25056954 |
| 2013-02-02 11:57:00 | Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor alpha and may have implications in late infantile Batten disease therapy | 22989886 |
| 2012-03-10 10:25:00 | TPPI activity becomes crucial for the neuronal functions later in development. | 21996941 |
| Type | IDs |
|---|---|
| Synonymous | Cln2, LPIC, TPP-1, TPP-I |
| Gene |
UniProtKB-ID:
TPP1_MOUSE
UniprotKB:
O89023
UniParc:
UPI000000150E
EMBL:
BC024820,
AF111172,
AK048279,
AK170781,
AF124599,
AK002418,
AJ011912
Ensembl:
ENSMUSG00000030894
KO:
mmu:12751
|
| Nucleutide sequences |
EMBL-CDS:
BAB22085.1,
AAD03083.1,
CAA09863.1,
BAC33293.1,
AAH24820.1,
BAE42026.1,
AAD32573.1
Ensembl_TRS:
ENSMUST00000033184
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033184
RefSeq:
NP_034036.1,
XP_011239970.1
|
| Others |
UniRef100:
UniRef100_O89023
UniRef90:
UniRef90_O89023
UniRef50:
UniRef50_O14773
UniGene:
Mm.20837
CCDS:
CCDS21661.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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