| Type | Description |
|---|---|
| Definition | CDC-like kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 12:43:00 | High CLK2 expression is associated with obesity. | 29575149 |
| 2017-07-15 11:54:00 | CLK2 is a regulatory component of diet-induced thermogenesis in brown adipose tissue. | 28089567 |
| 2014-06-14 10:20:00 | Liver-specific Clk2 knockout mice fed a high-fat diet exhibit increased fasting levels of blood ketone bodies, reduced respiratory exchange ratio, and increased gene expression of fatty acid oxidation and ketogenic pathways. | 24458359 |
| 2013-05-18 11:05:00 | LAMMER/Cdc2-like kinase, represented by Doa and its mammalian homolog CLK2, is a critical and conserved component in the regulatory program of the mitosis-to-meiosis switch | 23376537 |
| 2010-03-22 11:30:00 | Cdc2-like kinase 2 (Clk2) directly phosphorylates the SR domain on PGC-1alpha, resulting in repression of gluconeogenic gene expression and hepatic glucose output. | 20074525 |
| Type | IDs |
|---|---|
| Synonymous | AU041688 |
| Gene |
UniProtKB-ID:
CLK2_MOUSE,
F8WHX0_MOUSE
UniprotKB:
O35491,
F8WHX0
UniParc:
UPI0000193019,
UPI000164C489
EMBL:
AC161600,
AF033564
Ensembl:
ENSMUSG00000068917
KO:
mmu:12748
|
| Nucleutide sequences |
EMBL-CDS:
AAB87508.1
Ensembl_TRS:
ENSMUST00000121212,
ENSMUST00000090927
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113390,
ENSMUSP00000088445
RefSeq:
NP_031738.2,
NP_001156904.1
|
| Others |
UniRef100:
UniRef100_O35491,
UniRef100_F8WHX0
UniRef90:
UniRef90_O35491
UniRef50:
UniRef50_O35491
UniGene:
Mm.288098
CCDS:
CCDS17491.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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