| Type | Description |
|---|---|
| Definition | claudin 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-04 11:36:00 | In the hepatobiliary system, Cldn3 functions as a paracellular barrier for phosphate ions, and that dysfunction of this barrier causes significant dysfunctional biliary metabolism of phosphorus, which leads to the formation of calcium phosphate cores for cholesterol gallstones. | 30213590 |
| 2019-05-25 10:16:00 | Critical role of claudin-3 in water barrier function was confirmed in Cldn3-/- and Cldn3+/- mice and those with experimentally decreased claudin-3. Those results show the crucial role of claudin-3 in preventing sweat gland leakage and suggest that the pathogenesis of dermatoses accompanied by hypohidrosis involves abnormally decreased claudin-3. | 29277540 |
| 2019-04-20 10:47:00 | Crystal structure of claudin-3 explains claudin-3 interaction with the tight junction strands. | 30778075 |
| 2018-03-24 10:37:00 | Claudin-3 was present in the fila olfactoria from the epithelium to the olfactory nerve and in the main and accessory olfactory bulb. | 27943232 |
| 2017-07-01 10:58:00 | Reg I may play a role in the maintenance of mucosal barrier function by inducing tight junction proteins such as claudins 3 and 4. | 27055226 |
| Type | IDs |
|---|---|
| Synonymous | AI182374, Cpetr2, mRVP1 |
| Gene |
UniProtKB-ID:
CLD3_MOUSE,
Q545A5_MOUSE
UniprotKB:
Q9Z0G9,
Q545A5
UniParc:
UPI0000003E54,
UPI000002A6A9
EMBL:
AK012677,
AK002672,
AF095905,
AF087821,
BC012650
Ensembl:
ENSMUSG00000070473
KO:
mmu:12739
|
| Nucleutide sequences |
EMBL-CDS:
AAD14608.1,
AAH12650.1,
AAD09756.1,
BAB22275.1,
BAB28403.1
Ensembl_TRS:
ENSMUST00000094245
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000091799
RefSeq:
NP_034032.1
|
| Others |
UniRef100:
UniRef100_Q9Z0G9
UniRef90:
UniRef90_Q9Z0G9
UniRef50:
UniRef50_O15551
UniGene:
Mm.158662
CCDS:
CCDS19729.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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