| Type | Description |
|---|---|
| Definition | claudin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:26:00 | Inhibition of glycogen synthase kinase 3beta improves cognitive function in aged mice by upregulating claudin presences in cerebral endothelial cells. | 32141492 |
| 2020-09-19 16:29:00 | Holocrine Secretion Occurs outside the Barrier in Multicellular Glands: Lessons from Claudin-1-Deficient Mice. | 31445004 |
| 2020-05-30 11:31:00 | eosinophilic esophagitis (EoE) patient biopsy analysis identified a repressed HIF-1alpha/claudin-1 axis, which was restored via pharmacologic HIF-1alpha stabilization ex vivo. Collectively, these studies reveal HIF-1alpha's critical role in maintaining barrier and highlight the HIF-1alpha/claudin-1 axis as a potential therapeutic target for EoE. | 31264974 |
| 2019-12-21 10:39:00 | claudin-1 is incorporated in blood-brain barrier tight junction complex, impeding blood-brain barrier recovery and causing blood-brain barrier leakiness during poststroke recovery | 30504279 |
| 2019-07-13 11:24:00 | In SAMP10 mice, in addition to preventing a decrease in the naive T cell ratio, aging-associated skin thinning was suppressed histologically and the expression of representative tight junction genes, such as Claudin-1 and Zo-1, was increased. | 29964182 |
| Type | IDs |
|---|---|
| Synonymous | AI596271 |
| Gene |
UniProtKB-ID:
CLD1_MOUSE,
Q4FJV3_MOUSE
UniprotKB:
O88551,
Q4FJV3
UniParc:
UPI0000003F6D
EMBL:
CT010299,
AK040604,
AK028428,
AF072127,
AK054207,
AK081601,
AK036780,
AK036762,
BC002003
Ensembl:
ENSMUSG00000022512
KO:
mmu:12737
|
| Nucleutide sequences |
EMBL-CDS:
BAC30640.1,
BAC38267.1,
BAC29567.1,
AAC27078.1,
BAC29574.1,
BAC35693.1,
BAC25945.1,
AAH02003.1,
CAJ18507.1
Ensembl_TRS:
ENSMUST00000023154
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023154
RefSeq:
NP_057883.1
|
| Others |
UniRef100:
UniRef100_O88551
UniRef90:
UniRef90_O95832
UniRef50:
UniRef50_O95832
UniGene:
Mm.289441
CCDS:
CCDS28087.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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