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12683 Cidea

12683

Cidea

cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

protein-coding

Mus musculus

基因描述

Type Description
Definition cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

研究结论

Date Results Publications
2018-12-01 11:33:00 our findings suggest that Cidea is highly associated with alcoholic fatty liver disease and Cidea expression is specifically induced by acetaldehyde, and this up-regulation is most likely mediated by SREBP1c. 29352167
2017-07-08 11:00:00 results suggest that FSP27beta negatively regulates CideA-promoted enlargement of lipid droplet size in brown adipocytes. 28490632
2016-10-22 11:55:00 The authors show demonstrate an essential role of an amphipathic helix in CIDEA, which facilitates embedding in the lipid droplet phospholipid monolayer and binds phosphatidic acid (PA). 26609809
2016-08-06 10:31:00 Data (including data from studies in knockout mice) suggest Cideb promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea/Cidec promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice. 26733203
2016-04-23 11:01:00 Cidea is highly associated with adiposity and insulin resistance, whereas Cidec is related to insulin sensitivity 26176546

名称对应

Type IDs
Synonymous AW212747
Gene
UniProtKB-ID: CIDEA_MOUSE
UniprotKB: O70302
UniParc: UPI0000192DB9
EMBL: AC154125, BC096649, AF041376, CH466528
Ensembl: ENSMUSG00000024526
KO: mmu:12683
Nucleutide sequences
EMBL-CDS: EDL09650.1, AAH96649.1, AAC34985.1, EDL09649.1
Ensembl_TRS: ENSMUST00000025404
Protein sequencees
Ensembl_PRO: ENSMUSP00000025404
RefSeq: NP_031728.2
Others
UniRef100: UniRef100_O70302
UniRef90: UniRef90_O70302
UniRef50: UniRef50_O70302
UniGene: Mm.449
CCDS: CCDS37846.1

全选

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研究热度

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