| Type | Description |
|---|---|
| Definition | conserved helix-loop-helix ubiquitous kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:18:00 | Inducible knockout of CHUK/IKKalpha in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis. | 31222033 |
| 2019-11-02 13:27:00 | The data show that IKKa and IKKb regulate unique genes in pulmonary endothelial cells, resulting in differential effects on lung angiogenesis. | 29993183 |
| 2019-10-26 11:50:00 | our data reveals that IKKa is a novel mediator protecting against the development of myocardial I/R injury via negative regulation of macrophage polarization to M1 phenotype. | 30153439 |
| 2019-09-21 10:25:00 | Data suggest a direct link between microtubule-associated protein 1-light chain 3 (LC3)-associated phagocytosis (LAP) formation and IKK alpha (IKKalpha) recruitment downstream of -like receptor 9 (TLR9) activation that is necessary to facilitate type I IFN production. | 29717061 |
| 2019-08-17 12:37:00 | Data show that IkappaB kinase (IKK) controlled thymocyte survival by repressing cell-death-inducing activity of the serine/threonine kinase RIPK1 (RIPK1). | 30737145 |
| Type | IDs |
|---|---|
| Synonymous | AI256658, Chuk1, Fbx24, Fbxo24, IKBKA, IKK alpha, IKK1, Ikka, NFKBIKA |
| Gene |
UniProtKB-ID:
Q3TPN9_MOUSE,
E9Q605_MOUSE,
Q3UDK0_MOUSE,
E9QNL4_MOUSE,
Q8CBT3_MOUSE
UniprotKB:
Q3TPN9,
E9Q605,
Q3UDK0,
E9QNL4,
Q8CBT3
UniParc:
UPI0000022570,
UPI000161168D,
UPI00000E946D,
UPI00005B2049,
UPI00005AC957
EMBL:
AK035326,
AK164236,
AC124693,
AC125101,
AK150039
Ensembl:
ENSMUSG00000025199
KO:
mmu:12675
|
| Nucleutide sequences |
EMBL-CDS:
BAE37696.1,
BAE29261.1,
BAC29034.1
Ensembl_TRS:
ENSMUST00000119591,
ENSMUST00000026217
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113809,
ENSMUSP00000026217
RefSeq:
XP_030106592.1,
NP_001155882.1,
NP_031726.2
|
| Others |
UniRef100:
UniRef100_Q8CBT3,
UniRef100_E9QNL4,
UniRef100_Q3UDK0,
UniRef100_E9Q605,
UniRef100_Q3TPN9
UniRef90:
UniRef90_Q60680,
UniRef90_Q3UDK0,
UniRef90_Q95KV1
UniRef50:
UniRef50_O15111,
UniRef50_Q4G3H4
UniGene:
Mm.3996
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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