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12661 Chl1

12661

Chl1

cell adhesion molecule L1-like

protein-coding

Mus musculus

基因描述

Type Description
Definition cell adhesion molecule L1-like

研究结论

Date Results Publications
2021-01-23 13:01:00 Cell adhesion molecule close homolog of L1 binds to the dopamine receptor D2 and inhibits the internalization of its short isoform. 32052901
2021-01-02 12:50:00 CHL1 promotes insulin secretion and negatively regulates the proliferation of pancreatic beta cells. 32184019
2020-08-29 12:49:00 Close homolog of L1-deficient ameliorates inflammatory bowel disease by regulating the balance of Th17/Treg. 32640308
2020-06-27 10:07:00 Spine and excitatory synapse density of pyramidal neurons in the developing neocortex is regulated by CHL1. CHL1 mediated spine pruning in response to the secreted repellent ligand Semaphorin 3B and associated with receptor subunits Neuropilin-2 and PlexinA4. Loss of CHL1 in nullmice resulted in increased spine density and a greater proportion of immature spines on apical dendrites in the prefrontal and visual cortices. 31182634
2019-10-26 10:04:00 ADAM10 enhances BACE1-mediated CHL1 proteolysis. 29325091

名称对应

Type IDs
Synonymous A530023M13Rik, AI465420, CALL, LICAM2
Gene
UniProtKB-ID: NCHL1_MOUSE
UniprotKB: P70232
UniParc: UPI0000D62801, UPI00000EAD4F
EMBL: AJ319656, BC131671, BC131670, AC153598, AK053039, AK048639, AJ319657, AK040765, AC153595, AC161824, X94310, CH466523, AJ319655
Ensembl: ENSMUSG00000030077
KO: mmu:12661
Nucleutide sequences
EMBL-CDS: BAC30699.1, CAA63972.1, BAC33405.1, AAI31672.1, BAC35247.2, EDK99388.1, AAI31671.1, CAC88131.1
Ensembl_TRS: ENSMUST00000203830, ENSMUST00000203912, ENSMUST00000066905
Protein sequencees
Ensembl_PRO: ENSMUSP00000063933, ENSMUSP00000145026, ENSMUSP00000144758
RefSeq: XP_036021685.1, XP_030110991.1, XP_017176866.1, XP_006505530.1, XP_006505534.1, XP_036021688.1, XP_017176865.1, XP_030110992.1, XP_036021684.1, XP_006505532.1, XP_036021687.1, XP_006505536.1, XP_036021686.1, NP_031723.2, XP_006505535.1, XP_030110993.1, XP_011239500.1, XP_006505533.1
Others
UniRef100: UniRef100_P70232
UniRef90: UniRef90_P70232
UniRef50: UniRef50_P70232
UniGene: Mm.251288
CCDS: CCDS39582.1

全选

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