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12653 Chgb

12653

Chgb

chromogranin B

protein-coding

Mus musculus

基因描述

Type Description
Definition chromogranin B

研究结论

Date Results Publications
2019-03-02 11:32:00 Study using live-cell imaging at single vesicle resolution revealed a normal number of fusion events upon bursts of action potentials in CgA/B-/- neurons. Data indicate that the two chromogranins are dispensable for cargo sorting in the regulated secretory pathway and dense-core vesicle in mouse hippocampal neurons. 29178418
2015-12-19 10:55:00 This analysis of mice lacking Cgs highlights the important roles of CgA and CgB in glucose and cardiovascular homeostasis. This study also unveils the existence of direct implications of Cgs in the control of behaviour and mood. 25257107
2013-08-10 10:07:00 Chromogranin B contributes to a highly efficient system that directly mediates monoamine accumulation and exocytosis in large dense core secretory vesicles. 22415354
2012-03-03 11:43:00 Although chromogranins regulate the amine concentration in LDCVs, they are not completely essential. 21990378
2012-03-03 11:43:00 C-terminal domain of chromogranin B regulates intracellular calcium signaling. 22016391

名称对应

Type IDs
Synonymous Scg-1, cgB, sgI
Gene
UniProtKB-ID: SCG1_MOUSE, Q3TY66_MOUSE
UniprotKB: P16014, Q3TY66
UniParc: UPI00000014FC
EMBL: BC014736, X51429, AK158857, X53028
Ensembl: ENSMUSG00000027350
KO: mmu:12653
Nucleutide sequences
EMBL-CDS: AAH14736.1, CAA37199.1, CAA35792.1, BAE34697.1
Ensembl_TRS: ENSMUST00000028826
Protein sequencees
Ensembl_PRO: ENSMUSP00000028826
RefSeq: NP_031720.1
Others
UniRef100: UniRef100_P16014
UniRef90: UniRef90_P16014
UniRef50: UniRef50_P23389
UniGene: Mm.255241
CCDS: CCDS16777.1

全选

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研究热度

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