| Type | Description |
|---|---|
| Definition | calponin 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-18 11:14:00 | Study in human hepatocellular carcinoma cell line and xenograft mouse model shows that CNN2 plays an important role in tumor growth and metastasis, possibly through MEK1/2-ERK1/2 signaling pathway. | 29333089 |
| 2017-07-29 12:57:00 | our results demonstrated that knockdown of endogenous CNN2 in AGS cells could significantly activate cell apoptosis pathway and therefore suppress cell growth in vitro. The deletion of CNN2 might be a potential therapeutic approach to inhibit aggressive growth of gastric cancer. | 28714360 |
| 2015-04-18 12:11:00 | High Calponin-h2 serum levels are associated with breast cancer. | 25099617 |
| 2014-03-22 11:42:00 | h2-Calponin gene expression is further affected by the treatment of cells with Notch inhibitor and activator, suggesting an upstream signaling mechanism. | 24285540 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CNN2_HUMAN,
B4DDF4_HUMAN,
B4DUT8_HUMAN
UniprotKB:
Q99439,
B4DDF4,
B4DUT8
UniParc:
UPI00001405F0,
UPI00017A7FF4,
UPI0000127AF5,
UPI00017A6CB3
EMBL:
D86059,
CH471139,
AK126391,
AC004528,
D83735,
AC011558,
BC141833,
BC141818,
AK300788,
AK293171
Ensembl:
ENSG00000064666
KO:
hsa:1265
|
| Nucleutide sequences |
EMBL-CDS:
AAI41834.1,
AAI41819.1,
EAW69570.1,
BAA12090.1,
BAG54322.1,
EAW69567.1,
BAA20887.1,
EAW69565.1,
BAG56715.1,
BAG62450.1
Ensembl_TRS:
ENST00000348419,
ENST00000263097,
ENST00000565096,
ENST00000562958
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263097,
ENSP00000340129,
ENSP00000457968,
ENSP00000456436
RefSeq:
NP_958434.1,
NP_001290430.1,
NP_001290428.1,
NP_004359.1
|
| Others |
UniRef100:
UniRef100_B4DUT8,
UniRef100_Q99439,
UniRef100_B4DDF4
UniRef90:
UniRef90_Q99439,
UniRef90_B4DDF4,
UniRef90_B4DUT8
UniRef50:
UniRef50_Q15417,
UniRef50_Q99439
UniGene:
Hs.651512
CCDS:
CCDS12053.1,
CCDS12054.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员