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12649 Chek1

12649

Chek1

checkpoint kinase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition checkpoint kinase 1

研究结论

Date Results Publications
2020-10-31 13:20:00 CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos. 32914523
2020-10-03 12:50:00 CHK1 dosage in germinal center B cells controls humoral immunity. 30894677
2020-05-02 12:07:00 CHK1 inhibition kills primary mouse and human hematopoietic stem cells via BCL2-regulated apoptosis. 31379128
2019-04-20 11:39:00 An absence of 53BP1 leads to defective ATR-Chk1-p53 signaling. 29378830
2019-02-02 12:04:00 CHEK1 does not have a direct function in meiotic sex chromosome inactivation (MSCI), an essential event in male meiosis, in which ATR is a key regulator. 29360988

名称对应

Type IDs
Synonymous C85740, Chk1, rad27
Gene
UniProtKB-ID: CHK1_MOUSE
UniprotKB: O35280
UniParc: UPI00000239AF, UPI00005B2E74
EMBL: AK011258, AF016583, BC037613, AK033179, AK045336, AF032875
Ensembl: ENSMUSG00000032113
KO: mmu:12649
Nucleutide sequences
EMBL-CDS: AAH37613.1, BAC28185.1, BAC32315.1, AAC53334.1, BAB27500.1, AAB88853.1
Ensembl_TRS: ENSMUST00000034625, ENSMUST00000172702
Protein sequencees
Ensembl_PRO: ENSMUSP00000134388, ENSMUSP00000034625
RefSeq: XP_017168606.1, NP_031717.2
Others
UniRef100: UniRef100_O35280
UniRef90: UniRef90_O35280
UniRef50: UniRef50_O35280
UniGene: Mm.16753
CCDS: CCDS22972.1

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