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12648 Chd1

12648

Chd1

chromodomain helicase DNA binding protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition chromodomain helicase DNA binding protein 1

研究结论

Date Results Publications
2020-11-21 13:18:00 Organ-specific regulation of CHD1 by acute PTEN and p53 loss in mice. 32115152
2018-07-16 15:01:00 CHD1 loss is associated with an increased sensitivity to inhibition and anti-cancer drugs that induce DNA intercross-strand links in prostate tumors. 28383660
2016-01-30 11:11:00 These results underscore the importance of Chd1 for the regulation of pluripotency in ESCs and provide evidence for a hitherto unrecognized critical role of the phosphorylated N-terminal SRR for full functionality of Chd1. 25620209
2015-11-21 11:54:00 find that Chd1 evicts nucleosomes downstream of the promoter in order to overcome the nucleosomal barrier and enable PolII promoter escape, thus providing mechanistic insight into the role of Chd1 in transcription and pluripotency 24737864
2015-09-26 15:03:00 These findings indicate that CHD1 plays important roles in mouse early embryogenesis via activation of Hmgpi at zygotic gene activation. 26092847

名称对应

Type IDs
Synonymous 4930525N21Rik, AI851787, AW555109
Gene
UniProtKB-ID: CHD1_MOUSE
UniprotKB: P40201
UniParc: UPI0000192D4D
EMBL: L10410, CH466630, BC115822
Ensembl: ENSMUSG00000023852
KO: mmu:12648
Nucleutide sequences
EMBL-CDS: EDL20454.1, AAI15823.1, AAB08486.1
Ensembl_TRS: ENSMUST00000024627
Protein sequencees
Ensembl_PRO: ENSMUSP00000024627
RefSeq: NP_031716.2, XP_036016182.1
Others
UniRef100: UniRef100_P40201
UniRef90: UniRef90_O14646
UniRef50: UniRef50_O14646
UniGene: Mm.8137
CCDS: CCDS28416.1

全选

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研究热度

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