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12642 Ch25h

12642

Ch25h

cholesterol 25-hydroxylase

protein-coding

Mus musculus

基因描述

Type Description
Definition cholesterol 25-hydroxylase

研究结论

Date Results Publications
2019-11-30 10:18:00 Overexpression of both human and murine CH25H inhibited rabies virus (RABV) infection in HEK-293T cells. 31552533
2019-07-27 11:02:00 results indicate that osteoarthritis is a disease associated with metabolic disorders and suggest that targeting the CH25H-CYP7B1-RORalpha axis of cholesterol metabolism may provide a therapeutic avenue for treating osteoarthritis. 30728500
2017-06-24 11:59:00 Adenovirus-mediated Ch25h overexpression in mice improved glucose tolerance and insulin sensitivity and lowered HOMA-IR. Our data suggest that low hepatic Ch25h levels could be considered a risk marker for unhealthy obesity. 28299341
2014-08-30 11:21:00 Ch25h-deficient mice exhibit increased sensitivity to septic shock, exacerbated experimental autoimmune encephalomyelitis, and a stronger ability to repress bacterial growth. 25104388
2013-02-23 11:24:00 Disruption of Roralpha1 and cholesterol 25-hydroxylase expression attenuates phagocytosis in male Roralphasg/sg mice. 23239817

名称对应

Type IDs
Synonymous AI462618, m25OH
Gene
UniProtKB-ID: CH25H_MOUSE
UniprotKB: Q9Z0F5
UniParc: UPI0000024786
EMBL: AF059213, AK152770, BC039919, AF059211, AK160657, AK140360
Ensembl: ENSMUSG00000050370
KO: mmu:12642
Nucleutide sequences
EMBL-CDS: BAE24352.1, AAC97480.1, AAC97482.1, BAE31482.1, BAE35945.1, AAH39919.1
Ensembl_TRS: ENSMUST00000050562
Protein sequencees
Ensembl_PRO: ENSMUSP00000049683
RefSeq: NP_034020.1
Others
UniRef100: UniRef100_Q9Z0F5
UniRef90: UniRef90_Q9Z0F5
UniRef50: UniRef50_Q9Z0F5
UniGene: Mm.30824
CCDS: CCDS29759.1

全选

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研究热度

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