| Type | Description |
|---|---|
| Definition | WT1 interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway. | 33108271 |
| 2020-04-25 13:02:00 | WTIP impairs AKT phosphorylation and activation, leading to enhanced expression and transcriptional activity of FOXO1, which further increases p21Cip1 and p27Kip1, and decreases cyclin D1, which consequently results in cell cycle arrest. | 30690883 |
| 2019-09-21 12:19:00 | The findings suggest that the UBA2-WTIP fusion is an oncogenic fusion gene, as well as a promising therapeutic target for the treatment of acute myeloid leukemia. | 30179602 |
| 2019-09-14 12:27:00 | We show that all three mammalian Ajuba family proteins - AJUBA, LIMD1 and WTIP - exhibit tension-dependent localization to adherens junctions, and that both LATS family proteins, LATS1 and LATS2, exhibit an overlapping tension-dependent junctional localization | 29440237 |
| 2017-09-30 12:00:00 | WTIP interacts with BRCA2 and might be responsible for BRCA2 centrosome localization in cervical cancer cell. | 27535760 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
WTIP_HUMAN
UniprotKB:
A6NIX2
UniParc:
UPI00006C19C5
EMBL:
AC008747
Ensembl:
ENSG00000142279
KO:
hsa:126374
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000590071
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000466953
RefSeq:
XP_011524755.1,
XP_011524754.1,
XP_006723077.1,
NP_001073905.1
|
| Others |
UniRef100:
UniRef100_A6NIX2
UniRef90:
UniRef90_A6NIX2
UniRef50:
UniRef50_Q7TQJ8
UniGene:
Hs.585010
CCDS:
CCDS59375.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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