| Type | Description |
|---|---|
| Definition | leucine rich repeat containing 25 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 12:58:00 | LRRC25, a potential leukocyte differentiation antigen, is a key regulator of all-trans retinoic acid-induced granulocytic differentiation | 28536942 |
| 2019-07-06 11:21:00 | Our study has not only identified LRRC25 as a novel inhibitor of NF-kappaB signaling pathway, but also uncovers a new mechanism of crosstalk between NF-kappaB signaling and autophagy pathways. | 29044191 |
| 2019-05-25 11:28:00 | LRRC25 as a critical molecular switch whose down-regulation resulted in cardiac hypertrophy in a TGF-beta1- and NF-kappaB-dependent manner. | 30340835 |
| 2018-10-13 10:26:00 | The findings identify a previously unrecognized role of LRRC25 in type I interferon signaling activation by which LRRC25 acts as a secondary receptor to assist RIG-I delivery to autophagosomes for degradation in a p62-dependent manner. | 29288164 |
| Type | IDs |
|---|---|
| Synonymous | MAPA |
| Gene |
UniProtKB-ID:
LRC25_HUMAN
UniprotKB:
Q8N386
UniParc:
UPI000013EEF4
EMBL:
AJ422148,
BC093842,
AY358151,
AK095435,
BC071640
Ensembl:
ENSG00000175489
KO:
hsa:126364
|
| Nucleutide sequences |
EMBL-CDS:
AAH93842.1,
AAQ88518.1,
AAH71640.1,
CAD19531.1,
BAC04548.1
Gene_ORFName:
UNQ6169/PRO20174
Ensembl_TRS:
ENST00000339007,
ENST00000595840
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000340983,
ENSP00000472290
RefSeq:
NP_660299.2,
XP_005259796.1
|
| Others |
UniRef100:
UniRef100_Q8N386
UniRef90:
UniRef90_Q8N386
UniRef50:
UniRef50_Q8N386
UniGene:
Hs.332156
CCDS:
CCDS12377.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31068071 |
Autophagy Huifang Xian , Shuai Yang , Shouheng Jin , Yuxia Zhang , Jun Cui |
2020-03-01 | - |
| 30340835 |
Biochem. Biophys. Res. Commun. Xia Zhang , Ming-Chao Zhang , Chun-Tian Wang |
2018-11-17 | - |
| 28536942 |
Protein Cell Weili Liu , Ting Li , Pingzhang Wang , Wanchang Liu , Fujun Liu , Xiaoning Mo , Zhengyang Liu , Quansheng Song , Ping Lv , Guorui Ruan , Wenling Han |
2018-09-01 | - |
| 29288164 |
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation. EMBO J. Yang Du , Tianhao Duan , Yanchun Feng , Qingxiang Liu , Meng Lin , Jun Cui , Rong-Fu Wang |
2018-02-01 | - |
| 29044191 |
Sci Rep Yanchun Feng , Tianhao Duan , Yang Du , Shouheng Jin , Mingjun Wang , Jun Cui , Rong-Fu Wang |
2017-10-18 | - |
| 21044950 |
Mol Cell Proteomics Ok-Hee Lee , Hyeung Kim , Quanyuan He , Hwa Jin Baek , Dong Yang , Liuh-Yow Chen , Jiancong Liang , Heekyung Kate Chae , Amin Safari , Dan Liu , Zhou Songyang |
2011-02-01 | - |
| 17207965 |
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics Philippe Lamesch , Ning Li , Stuart Milstein , Changyu Fan , Tong Hao , Gabor Szabo , Zhenjun Hu , Kavitha Venkatesan , Graeme Bethel , Paul Martin , Jane Rogers , Stephanie Lawlor , Stuart McLaren , Amélie Dricot , Heather Borick , Michael E Cusick , Jean Vandenhaute , Ian Dunham , David E Hill , Marc Vidal |
2007-03-01 |
GNPDA1,
CTAGE4,
BCL2L11,
PIGK,
TIMM23,
NPIPA5,
CST8,
AP1M2,
COX17,
TIMM23B,
SNX29P1,
IL18BP,
RWDD2B,
TSSC4,
UPK1A-AS1,
ARPC5,
ARPC3,
TSPAN5,
TSPAN3,
TSPAN1,
PPIF,
CTDSP2,
NAMPT,
PDZK1IP1,
DHRS9,
RBM7,
MPHOSPH6,
DHRS2,
MPZL2,
GPA33,
CALCOCO2,
SPRY3,
SPRY1,
RAMP3,
TRAIP,
DNAJA2,
IKZF1,
CRISP3,
SIRPB1,
CNPY2,
B3GNT3,
WARS2,
NPM3,
CDO1,
CACNG3,
TUBB4B,
CEPT1,
PEMT,
WFDC2,
NSA2,
EMG1,
TIMM17A,
PPIE,
HAX1,
CIB2,
DCTN2,
RPP38,
SLC35A1,
IFI44,
CXCL13,
SIVA1,
MRPL28,
CENPA,
MAB21L2,
RAD51AP1,
MTX2,
CGRRF1,
DCTN6,
B3GNT2,
CLDN16,
PNMA2,
KLRA1P,
SRSF10,
ARPP21,
STARD10,
CGA,
EDDM3A,
CFHR3,
GPR83,
RAB10,
CPSF4,
RUNDC3A,
COPS8,
C11orf58,
CCDC85B,
GLIPR1,
KLK11,
SNRNP27,
LIAS,
LILRA2,
SNRNP35,
CYB561D2,
ESM1,
WDR5,
BTN2A1,
HHLA3,
BVES,
KLK8,
MRPL3
|
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 12975309 |
Genome Res. Hilary F Clark , Austin L Gurney , Evangeline Abaya , Kevin Baker , Daryl Baldwin , Jennifer Brush , Jian Chen , Bernard Chow , Clarissa Chui , Craig Crowley , Bridget Currell , Bethanne Deuel , Patrick Dowd , Dan Eaton , Jessica Foster , Christopher Grimaldi , Qimin Gu , Philip E Hass , Sherry Heldens , Arthur Huang , Hok Seon Kim , Laura Klimowski , Yisheng Jin , Stephanie Johnson , James Lee , Lhney Lewis , Dongzhou Liao , Melanie Mark , Edward Robbie , Celina Sanchez , Jill Schoenfeld , Somasekar Seshagiri , Laura Simmons , Jennifer Singh , Victoria Smith , Jeremy Stinson , Alicia Vagts , Richard Vandlen , Colin Watanabe , David Wieand , Kathryn Woods , Ming-Hong Xie , Daniel Yansura , Sothy Yi , Guoying Yu , Jean Yuan , Min Zhang , Zemin Zhang , Audrey Goddard , William I Wood , Paul Godowski , Alane Gray |
2003-10-01 |
Sdhd,
SIGLEC14,
LOC100127951,
LOC100128035,
LOC100128644,
LOC100128816,
LPEQ6126,
QIQN5815,
UNQ6494,
EPWW6493,
LOC100130071,
LOC100130428,
LRRC70,
LOC100130916,
LOC100131131,
CD300LD,
LOC100131541,
LOC100131826,
LOC100131943,
LOC100132099,
LOC100133106,
C17orf99,
INSL5,
PET117,
TOM1,
SH2D3C,
SH2D3A,
LOC100506242,
CASP12,
HCG8,
LOC100507646,
LOC100508226,
FAM24B-CUZD1,
GPC6,
PINK1-AS,
PPIF,
CDH16,
CLEC3A,
DHRS9,
CNIH1,
MPZL2,
ANGPTL7,
LRRC17,
FSTL3,
CWC27,
CNPY2,
B3GNT3,
CCL26,
PRG3,
SPON2,
LRRN2,
GPNMB,
SEMA6B,
SEMA4B,
FBLN5,
LOC105377021,
AGR2,
OLFM4,
COLEC10,
LEFTY1,
TNFSF13B,
CNPY3,
YME1L1,
ARID5A,
HCST,
LYVE1,
DHRS4,
UTS2,
BTNL3,
PRSS21,
SLC27A3,
KLK11,
ADAM30,
ADAMTS13,
CACFD1,
PRSS23,
CLASRP,
FICD,
ERLIN2,
WIF1,
KLK8,
NXPH4,
NXPH3,
MAN1B1,
RDH13,
GLMP,
MGAT4B,
B4GALT7,
CFAP36,
IZUMO4,
CHST14,
CASC4,
VSIG4,
SCRG1,
TEX261,
SIGLEC11,
LACTB,
PGLYRP2,
SLC25A25
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员