| Type | Description |
|---|---|
| Definition | mitotic spindle positioning |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 12:06:00 | MISP directly interacts with ezrin and that SLK/LOK-activated ezrin ensures appropriate cortical MISP levels in mitosis by competing with MISP for actin-binding sites at the cell cortex. | 29669740 |
| 2014-10-11 12:21:00 | MISP is an effector for cell type-specific actin reorganization with its direct actin-binding properties and provides a novel model of cell morphology regulation by a non-ubiquitous single actin-bundling protein. | 24475924 |
| 2014-07-07 16:10:00 | Bundles F-actin and balances stress fiber-filopodial formation | 24475924 |
| 2013-12-07 11:19:00 | MISP links microtubules to the actin cytoskeleton and focal adhesions in order to properly position the mitotic spindle. | 23574715 |
| 2013-06-01 11:48:00 | Plk1 phosphorylates MISP, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. | 23509069 |
| Type | IDs |
|---|---|
| Synonymous | C19orf21, MISP1 |
| Gene |
UniProtKB-ID:
MISP_HUMAN
UniprotKB:
Q8IVT2
UniParc:
UPI00000745CD
EMBL:
BC052236,
BC042125
Ensembl:
ENSG00000099812
KO:
hsa:126353
|
| Nucleutide sequences |
EMBL-CDS:
AAH42125.1,
AAH52236.1
Ensembl_TRS:
ENST00000215582
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000215582
RefSeq:
XP_011525987.1,
XP_011525988.1,
NP_775752.1
|
| Others |
UniRef100:
UniRef100_Q8IVT2
UniRef90:
UniRef90_Q8IVT2
UniRef50:
UniRef50_Q8IVT2
UniGene:
Hs.439180
CCDS:
CCDS12042.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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