| Type | Description |
|---|---|
| Definition | cofilin 2, muscle |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | CFL2 is an essential mediator for myogenic differentiation in C2C12 myoblasts. | 33187645 |
| 2020-03-28 11:19:00 | Actin depolymerizing factor (ADF)/cofilin controls actin turnover to sustain axon regeneration after spinal cord injury through its actin-severing activity. This pinpoints ADF/cofilin as a key regulator of axon growth competence, irrespective of developmental stage. | 31400829 |
| 2019-06-08 12:02:00 | Results provide strong evidence that muscle-type cofilin (or cofilin-2) plays a critical role in the formation and the maintenance of myofibril structure not only in skeletal muscle but also in cardiac muscle. | 31120645 |
| 2018-07-21 10:47:00 | These results indicated that the mouse CFL2 gene may be involved in the regulation of MyHC via the key signaling molecules of CFL2-related signaling pathways. | 29207028 |
| 2017-11-04 12:40:00 | miR-301a regulates Cofilin-2 in vitro in NRVCM, and in vivo in Cs1-ko mice. Our findings provide an additional and important layer of Cfl2 regulation, which we believe has an extended role in cardiac signal transduction and dilated cardiomyopathy presumably due to the reported involvement of Cfl2 in these mechanisms. | 28886070 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
COF2_MOUSE,
Q3UHW9_MOUSE
UniprotKB:
P45591,
Q3UHW9
UniParc:
UPI00000297BD
EMBL:
BC007138,
L29468,
AK147174
Ensembl:
ENSMUSG00000062929
KO:
mmu:12632
|
| Nucleutide sequences |
EMBL-CDS:
AAH07138.1,
AAA37433.1,
BAE27737.1
Ensembl_TRS:
ENSMUST00000078124
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077262
RefSeq:
XP_006515515.1,
NP_031714.1
|
| Others |
UniRef100:
UniRef100_P45591
UniRef90:
UniRef90_Q9Y281
UniRef50:
UniRef50_Q9Y281
UniGene:
Mm.276826
CCDS:
CCDS36448.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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