| Type | Description |
|---|---|
| Definition | cofilin 1, non-muscle |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:22:00 | Cofilin 1 promotes the aggregation and cell-to-cell transmission of alpha-synuclein in Parkinson's disease. | 32819564 |
| 2020-12-05 13:03:00 | Cofilin dysregulation alters actin turnover in frataxin-deficient neurons. | 32251310 |
| 2020-11-21 13:19:00 | FMRP Modulates Activity-Dependent Spine Plasticity by Binding Cofilin1 mRNA and Regulating Localization and Local Translation. | 30953439 |
| 2020-04-25 11:37:00 | Global inhibition of neddylation in developing neurons leads to cytoskeletal defects, altered actin dynamics and neurite growth impairments, whereas site-specific neddylation of cofilin 1 at K112 regulates neurite outgrowth, suggesting that cofilin 1 neddylation contributes to the regulation of neuronal actin organization. | 32015554 |
| 2020-03-28 11:19:00 | Actin depolymerizing factor (ADF)/cofilin controls actin turnover to sustain axon regeneration after spinal cord injury through its actin-severing activity. This pinpoints ADF/cofilin as a key regulator of axon growth competence, irrespective of developmental stage. | 31400829 |
| Type | IDs |
|---|---|
| Synonymous | AA959946, Cof |
| Gene |
UniProtKB-ID:
COF1_MOUSE,
Q544Y7_MOUSE
UniprotKB:
P18760,
Q544Y7
UniParc:
UPI0000003F10
EMBL:
AK088793,
D00472,
AK088633,
AK167795,
BC058726,
AK050651,
BC046225,
AK013943,
BC094357
Ensembl:
ENSMUSG00000056201
KO:
mmu:12631
|
| Nucleutide sequences |
EMBL-CDS:
BAA00364.1,
AAH58726.1,
AAH46225.1,
BAE39825.1,
BAC40575.1,
BAC34363.1,
BAC40467.1,
AAH94357.1,
BAB29074.1
Ensembl_TRS:
ENSMUST00000209469
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000147514
RefSeq:
NP_031713.1
|
| Others |
UniRef100:
UniRef100_P18760
UniRef90:
UniRef90_P18760
UniRef50:
UniRef50_P18760
UniGene:
Mm.329655
CCDS:
CCDS84409.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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