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126259 TMIGD2

126259

TMIGD2

transmembrane and immunoglobulin domain containing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition transmembrane and immunoglobulin domain containing 2

研究结论

Date Results Publications
2020-08-01 11:04:00 VISTA protein (B7-H5) is a ligand for transmembrane and immunoglobulin domain containing 2 protein (CD28H) and is widely expressed in tumor cells. B7-H5 expression is closely related to the prognosis of the tumor [Review]. 31901178
2020-05-16 11:51:00 Findings indicate that IGPR-1 is an important player in endothelial cell mechanosensing, insights that have important implications for the pathogenesis of common maladies, including ischemic heart diseases and inflammation. 31341021
2019-08-31 12:57:00 High TMIGD2 expression levels in oral squamous cell carcinoma cells indicate poor prognosis. TMIGD2 expression inversely correlated with the TIM3, LAG3, and B7H3 levels. 31089395
2019-02-16 10:05:00 B7-H5/CD28H is a co-stimulatory signal pathway, and expression of B7-H5 is associated with improved disease prognosis in patients with pancreatic cancer. 30548441
2017-07-01 10:06:00 The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. 27838321

名称对应

Type IDs
Synonymous CD28H, IGPR-1, IGPR1
Gene
UniProtKB-ID: TMIG2_HUMAN, A0A0B4J2A9_HUMAN
UniprotKB: Q96BF3, A0A0B4J2A9
UniParc: UPI00020B1165, UPI00000477FC, UPI000013E6F4
EMBL: AC008616, AY358964, BC015655
Ensembl: ENSG00000167664
KO: hsa:126259
Nucleutide sequences
EMBL-CDS: AAH15655.1, AAQ89323.1
Gene_ORFName: UNQ3059/PRO9879
Ensembl_TRS: ENST00000301272, ENST00000595645, ENST00000600114
Protein sequencees
Ensembl_PRO: ENSP00000301272, ENSP00000470561, ENSP00000470494
RefSeq: XP_024307127.1, NP_001162597.1, NP_001295161.1, XP_016881773.1, NP_653216.2
Others
UniRef100: UniRef100_Q96BF3, UniRef100_A0A0B4J2A9
UniRef90: UniRef90_A0A0B4J2A9, UniRef90_Q96BF3
UniRef50: UniRef50_A0A0B4J2A9, UniRef50_Q96BF3
UniGene: Hs.263928
CCDS: CCDS59334.1, CCDS12126.1

全选

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