| Type | Description |
|---|---|
| Definition | NLR family pyrin domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:51:00 | The identification of two novel maternal-effect variants of NLRP5 associated with poly-abortivity and s multi-locus imprinting disturbances (MLID) adds further evidence to its role in the maintenance of genomic imprinting in early embryos. | 31829238 |
| 2020-06-06 12:45:00 | NLRP2 and NLRP5 are novel mutant genes responsible for human early embryonic arrest. | 30877238 |
| 2017-09-02 10:14:00 | PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS. | 28501589 |
| 2017-02-18 12:23:00 | expression of MATER and NOX4 proteins are closely related to the follicular development and ovulation with particular regard for ovarian aging | 27515505 |
| 2016-04-30 11:24:00 | NLRP5 mutation is associated with multilocus imprinting disorders and reproductive wastage. | 26323243 |
| Type | IDs |
|---|---|
| Synonymous | CLR19.8, MATER, NALP5, PAN11, PYPAF8 |
| Gene |
UniProtKB-ID:
NALP5_HUMAN
UniprotKB:
P59047
UniParc:
UPI00001AEEBD
EMBL:
AY154460,
AC024580,
AC011470,
AY054986
Ensembl:
ENSG00000171487
KO:
hsa:126206
|
| Nucleutide sequences |
EMBL-CDS:
AAO18156.1,
AAL15549.1
Ensembl_TRS:
ENST00000390649
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000375063
RefSeq:
NP_703148.4
|
| Others |
UniRef100:
UniRef100_P59047
UniRef90:
UniRef90_P59047
UniRef50:
UniRef50_P59047
UniGene:
Hs.356872
CCDS:
CCDS12938.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员