| Type | Description |
|---|---|
| Definition | carnitine palmitoyltransferase 1C |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:53:00 | Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. | 32289751 |
| 2020-06-13 10:32:00 | We demonstrate in HeLa cells that carnitine palmitoyltransferase 1C (CPT1C) senses malonyl-CoA and enhances LE/Lys anterograde transport by interacting with the endoplasmic reticulum protein protrudin and facilitating the transfer of Kinesin-1 from protrudin to LE/Lys | 31868590 |
| 2019-12-14 12:15:00 | CPT1C exerts the most significant effect on mitochondrial dysfunction-associated tumor cellular senescence among the members of the carnitine palmitoyltransferases family. | 30070697 |
| 2019-10-12 11:16:00 | These results indicate that CPT1C-mediated autophagy enhancement in glucose deprivation conditions allows a greater availability of lipids to be used as fuel substrate for ATP generation, revealing a new role of CPT1C in stem cell adaptation to low nutrient environments. | 29725060 |
| 2019-09-14 12:44:00 | This study identifies CPT1C as a novel biomarker and key regulator of cancer cell senescence through mitochondria-associated metabolic reprograming, and suggests that inhibition of CPT1C may represent a new therapeutic strategy for cancer treatment through induction of tumor senescence. | 29317762 |
| Type | IDs |
|---|---|
| Synonymous | CATL1, CPT1-B, CPT1P, CPTI-B, CPTIC, SPG73 |
| Gene |
UniProtKB-ID:
CPT1C_HUMAN,
A0A024QZE3_HUMAN,
B3KU49_HUMAN,
A0A024QZI3_HUMAN
UniprotKB:
Q8TCG5,
A0A024QZE3,
B3KU49,
A0A024QZI3
UniParc:
UPI0000072DBD,
UPI000049E304,
UPI0000071C78,
UPI00003E5F73
EMBL:
AF331918,
AK096516,
BC029104,
AF357970,
CH471177,
AL831876,
AK290092,
AK289713,
AK074389
Ensembl:
ENSG00000169169
KO:
hsa:126129
|
| Nucleutide sequences |
EMBL-CDS:
BAF82402.1,
AAH29104.1,
CAD38561.2,
EAW52524.1,
BAB85068.1,
BAF82781.1,
AAQ14875.1,
AAL99615.1,
EAW52528.1,
BAG53311.1,
EAW52526.1,
EAW52523.1,
EAW52530.1
Gene_ORFName:
hCG_2039825,
hCG_2039825,
hCG_2039825
Ensembl_TRS:
ENST00000405931,
ENST00000323446,
ENST00000392518,
ENST00000598293
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000473028,
ENSP00000376303,
ENSP00000319343,
ENSP00000384465
RefSeq:
NP_001129524.1,
NP_001365415.1,
XP_024307126.1,
NP_001186681.1,
XP_024307121.1,
NP_001365417.1,
XP_006723072.1,
XP_016881756.1,
XP_024307119.1,
XP_024307122.1,
XP_016881761.1,
XP_024307116.1,
XP_016881758.1,
XP_024307125.1,
NP_001365413.1,
XP_024307124.1,
XP_016881762.1,
XP_024307118.1,
NP_689572.1,
XP_024307117.1,
XP_024307120.1,
NP_001365412.1,
NP_001365411.1,
NP_001186682.1,
NP_001365414.1,
XP_016881757.1,
NP_001365416.1,
XP_016881760.1
|
| Others |
UniRef100:
UniRef100_Q8TCG5,
UniRef100_A0A024QZI3
UniRef90:
UniRef90_Q8TCG5,
UniRef90_A0A2K6P1K3
UniRef50:
UniRef50_Q8TCG5
UniGene:
Hs.112195
CCDS:
CCDS46147.1,
CCDS12779.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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