| Type | Description |
|---|---|
| Definition | cyclin dependent kinase inhibitor 2B |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis. | 33824349 |
| 2021-02-20 13:29:00 | Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice. | 32271879 |
| 2019-07-27 11:12:00 | DNMT1-mediated DNA hypermethylation can enhance the process of corneal epithelial wound healing by directly targeting miR-200a and CDKN2B. | 30785991 |
| 2019-05-04 11:00:00 | These results point to a critical role of the Cdkn2ab locus in keeping the oncogenic potential of physiological levels of WNT signaling in check. | 30926782 |
| 2018-10-20 11:13:00 | Pancreatic cancer was induced in adult mice by the combination of KRASG12D overexpression and loss of Tp53 and Cdkn2a only if Cdkn2b was concomitantly inactivated. inactivation of both Cdkn2b and Cdkn2a was necessary for Rb phosphorylation and to encompass oncogene-induced cellular senescence. | 28892048 |
| Type | IDs |
|---|---|
| Synonymous | AV083695, INK4b, MTS2, p15, p15(INK4b), p15INK4b |
| Gene |
UniProtKB-ID:
CDN2B_MOUSE,
Q549R4_MOUSE
UniprotKB:
P55271,
Q549R4
UniParc:
UPI000000018D
EMBL:
BC002010,
U66084,
AF059567,
U66085
Ensembl:
ENSMUSG00000073802
KO:
mmu:12579
|
| Nucleutide sequences |
EMBL-CDS:
AAH02010.1,
AAB39833.1,
AAC14569.1
Ensembl_TRS:
ENSMUST00000097981
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095595
RefSeq:
NP_031696.1
|
| Others |
UniRef100:
UniRef100_P55271
UniRef90:
UniRef90_P55271
UniRef50:
UniRef50_P55271
UniGene:
Mm.423094
CCDS:
CCDS18351.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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