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12577 Cdkn1c

12577

Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

protein-coding

Mus musculus

基因描述

Type Description
Definition cyclin-dependent kinase inhibitor 1C (P57)

研究结论

Date Results Publications
2020-11-21 13:25:00 Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development. 32024956
2020-04-04 11:43:00 Cdkn1c locus regulates cortical development through distinct cell-autonomous and non-cell-autonomous mechanisms. 31924768
2019-06-29 10:38:00 The results reveal a novel Shh-Foxd1-Cdkn1c regulatory circuit that drives the mitogenic action of Shh signaling. Shh pathway activation of Foxd1 is followed by downregulation of Cdkn1c, which encodes a cyclin-dependent kinase inhibitor. 29284139
2019-05-11 11:01:00 Here we show that loss of Ezh2 resulted in altered expression of several key cyclin-dependent kinase inhibitors including Cdkn2a (p16 and Arf) and Cdkn1c (p57) in naive CD8+ T cells after activation, which explained the cell cycle impairment of Ezh2-deficient naive CD8+ T cells in response to antigenic stimulation. 29632530
2019-01-12 11:41:00 We propose that CDKN1c activity is restricted to differentiating myoblasts by regulated cyto-nuclear relocalization, coordinating the balance between proliferation and growth arrest. 30284969

名称对应

Type IDs
Synonymous AL024410, CDKI, Kip2, p57(kip2), p57Kip2
Gene
UniProtKB-ID: CDN1C_MOUSE, Q791X1_MOUSE
UniprotKB: P49919, Q791X1
UniParc: UPI00000242BB, UPI00001C3F5A
EMBL: U22399, CH466531, U20553, AC023248, AF160190, BC005412
Ensembl: ENSMUSG00000037664
KO: mmu:12577
Nucleutide sequences
EMBL-CDS: AAC52186.1, EDL18208.1, AAA85096.1, AAH05412.1, AAF00983.1
Ensembl_TRS: ENSMUST00000167912, ENSMUST00000037287
Protein sequencees
Ensembl_PRO: ENSMUSP00000128828, ENSMUSP00000037302
RefSeq: NP_001341910.1, XP_006508531.1, XP_006508530.1, NP_034006.3, XP_006508533.1, XP_030097907.1, XP_030097905.1, XP_030097906.1, XP_030097908.1, XP_006508532.1, NP_001155096.1, XP_030097904.1
Others
UniRef100: UniRef100_P49919
UniRef90: UniRef90_P49919
UniRef50: UniRef50_P49918
UniGene: Mm.168789
CCDS: CCDS52463.1, CCDS22040.1

全选

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