例如:"NBL1", "4681", "drought"
收藏
12571 Cdk6

12571

Cdk6

cyclin-dependent kinase 6

protein-coding

Mus musculus

基因描述

Type Description
Definition cyclin-dependent kinase 6

研究结论

Date Results Publications
2021-03-13 13:24:00 CDK6 inhibition targeted by miR-378a-3p protects against intestinal injury induced by ionizing radiation. 32800335
2021-02-27 13:49:00 CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia. 32344427
2021-02-20 13:35:00 The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. 32701505
2021-02-06 13:58:00 CDK4/6 Dependence of Cyclin D1-Driven Parathyroid Neoplasia in Transgenic Mice. 32877917
2019-12-21 10:51:00 CDK6 acts at the interface of p53 and RB by driving cell-cycle progression and antagonizing stress responses. While sensitizing cells to p53-induced cell death, specific inhibition of CDK6 kinase activity may provoke the outgrowth of p53-mutant clones from premalignant cells. 29899063

名称对应

Type IDs
Synonymous AI504062, Crk2
Gene
UniProtKB-ID: CDK6_MOUSE, Q0VBK8_MOUSE
UniprotKB: Q64261, Q0VBK8
UniParc: UPI0000029435
EMBL: AF132482, AK078973, BC120595, AF132483, BC119360, X65068
Ensembl: ENSMUSG00000040274
KO: mmu:12571
Nucleutide sequences
EMBL-CDS: CAA46201.1, AAD43504.1, BAC37489.1, AAD43503.1, AAI20596.1, AAI19361.1
Ensembl_TRS: ENSMUST00000042410, ENSMUST00000165117
Protein sequencees
Ensembl_PRO: ENSMUSP00000126024, ENSMUSP00000037925
RefSeq: NP_034003.1, XP_030109951.1
Others
UniRef100: UniRef100_Q64261
UniRef90: UniRef90_Q64261
UniRef50: UniRef50_Q64261
UniGene: Mm.31672, Mm.389058, Mm.399714
CCDS: CCDS19062.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员