| Type | Description |
|---|---|
| Definition | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | p39-associated Cdk5 activity regulates dendritic morphogenesis. | 33127972 |
| 2018-09-08 11:54:00 | that the knockout of p39 in mice did not affect orofacial and peripheral nociception | 28969475 |
| 2017-07-22 10:21:00 | In this study, we discovered that selective upregulation of p39 is the underlying mechanism that accommodates the increased functional requirement of Cdk5 activation during neuronal differentiation. In addition, we demonstrated that p39 selectively directs Cdk5 to phosphorylate protein substrates essential for axonal development, dendritic spine formation, and synaptogenesis. Moreover, our studies suggest opposing roles o | 27807169 |
| 2016-07-30 11:47:00 | These data suggest p35 and p39 have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 activation. | 26961956 |
| 2014-10-04 10:58:00 | it was found that Tyr-15 phosphorylation occurred only on monomeric Cdk5, and the coexpression of activators, p35/p25, p39, or Cyclin I, inhibited the phosphorylation. | 24872417 |
| Type | IDs |
|---|---|
| Synonymous | B230310J22Rik, p39 |
| Gene |
UniProtKB-ID:
CD5R2_MOUSE
UniprotKB:
O35926
UniParc:
UPI000002528F
EMBL:
CH466548,
AF016393,
AF071086,
U90267
Ensembl:
ENSMUSG00000090071
KO:
mmu:12570
|
| Nucleutide sequences |
EMBL-CDS:
AAF14854.1,
AAC53595.1,
AAB69709.1,
EDL00353.1
Ensembl_TRS:
ENSMUST00000160379
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125322
RefSeq:
NP_034002.2
|
| Others |
UniRef100:
UniRef100_O35926
UniRef90:
UniRef90_O35926
UniRef50:
UniRef50_O35926
UniGene:
Mm.153833
CCDS:
CCDS48290.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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