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12569 Cdk5r1

12569

Cdk5r1

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

protein-coding

Mus musculus

基因描述

Type Description
Definition cyclin-dependent kinase 5, regulatory subunit 1 (p35)

研究结论

Date Results Publications
2020-10-03 12:54:00 AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain. 31256130
2020-09-26 13:04:00 p35 Hemizygous Deletion in 5xFAD Mice Increases Abeta Plaque Load in Males but Not in Females. 31421203
2019-12-07 10:09:00 Restoration of p35 expression in the hippocampus and cortex of Men1 conditional knockout mice rescues synaptic and cognitive deficits associated with Men1 deletion. 30021166
2018-03-10 10:30:00 This study demonstrated that a complete deletion of p35 normalized the accelerating Rotarod performance relative to their non-transgenic littermates at four months of age. 28391013
2017-05-20 10:08:00 It suggests that ectopic increase of Cdk5 kinase activity through conversion of p35 to p25 is involved in the process of neuronal death induced by hypoxia. 27402274

名称对应

Type IDs
Synonymous Cdk5r, D11Bwg0379e, p25, p35
Gene
UniProtKB-ID: CD5R1_MOUSE, Q542T9_MOUSE
UniprotKB: P61809, Q542T9
UniParc: UPI0000000283
EMBL: AK079557, Y11335, AF121847, BC050768, AK169667, BC046823, S82819, U89527, AK141549, BC058697
Ensembl: ENSMUSG00000048895
KO: mmu:12569
Nucleutide sequences
EMBL-CDS: AAH50768.1, AAB46777.1, CAA72176.1, AAH58697.1, AAB49474.1, AAH46823.1, BAE41289.1, BAE24731.1, BAC37683.1, AAD21195.1
Ensembl_TRS: ENSMUST00000053413
Protein sequencees
Ensembl_PRO: ENSMUSP00000099514
RefSeq: NP_034001.1
Others
UniRef100: UniRef100_P61809
UniRef90: UniRef90_Q15078
UniRef50: UniRef50_Q15078
UniGene: Mm.142275, Mm.474282
CCDS: CCDS25134.1

全选

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