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1255257 pyrE

1255257

pyrE

orotate phosphoribosyltransferase

protein-coding

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

基因描述

Type Description
Definition orotate phosphoribosyltransferase

研究结论

Date Results Publications
2017-11-04 12:49:00 PyrE is a virulence factor necessary for the de novo pyrimidine synthesis and intestinal colonization of Salmonella Typhimurium in chicks. 29040285
2012-12-08 10:06:00 In contrast to dimagnesium hypoxanthine-guanine phosphoribosyltransferases, orotate phosphoribosyltransferase synthase contains a single catalytic Mg(2+) in the closed active site. 22531064
2012-12-08 10:06:00 In this study, each of the residues of the catalytic loop of S. typhimurium orotate phosphoribosyltransferase synthase were mutated. The mutant enzymes show a range of catalytic lesion, from slight increases in kcat to a 105-fold reduction. 22531099

名称对应

Type IDs
Gene
UniProtKB-ID: PYRE_SALTY
UniprotKB: P08870
UniParc: UPI0000112436
EMBL: AE006468, Z19547
EnsemblGenome: STM3733
KO: stm:STM3733
Nucleutide sequences
EMBL-CDS: AAL22592.1, CAA79607.1
EnsemblGenome_TRS: AAL22592
Protein sequencees
EnsemblGenome_PRO: AAL22592
RefSeq: NP_462633.1
Others
UniRef100: UniRef100_Q57IA0
UniRef90: UniRef90_Q8XD99
UniRef50: UniRef50_Q8XD99

全选

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