| Type | Description |
|---|---|
| Definition | Rho GTPase activating protein 31 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 11:52:00 | findings are the first to demonstrate the importance of CdGAP in embryonic vascular development and VEGF-induced signaling, and highlight CdGAP as a potential therapeutic target to treat pathological angiogenesis and vascular dysfunction | 27270835 |
| 2011-05-28 10:50:00 | Increased levels of endogenous CdGAP in mammary tumor explant cells resulted in increased cell motility and invasion in response to TGF-beta, and downregulation by siRNA inhibited cell motility and invasion. CdGAP is required for TGF-beta effects. | 21042277 |
| 2011-05-21 10:24:00 | Data show that intersectin-SH3D interacts directly with a small region of CdGAP highly enriched in basic residues and comprising a novel conserved xKx(K/R)K motif. | 21349274 |
| 2010-01-21 00:00:00 | CdGAP is a novel substrate of extracellular signal-regulated kinase (ERK)1/2 and mediates cross talk between the Ras/mitogen-activated protein kinase pathway and regulation of Rac1 activity. | 16024771 |
| 2010-01-21 00:00:00 | Nudel facilitates cell migration by sequestering Cdc42GAP at the leading edge to stabilize active Cdc42 in response to extracellular stimuli. | 18331715 |
| Type | IDs |
|---|---|
| Synonymous | 5830477L08Rik, AU041750, Cdgap, D330026I07Rik |
| Gene |
UniProtKB-ID:
RHG31_MOUSE,
B2RSI0_MOUSE
UniprotKB:
A6X8Z5,
B2RSI0
UniParc:
UPI0000215985
EMBL:
AK129309,
AK138417,
AK166622,
AK155729,
CT009576,
AF151363,
BC138870,
AK150109,
AC154425,
AK149975,
AK166583
Ensembl:
ENSMUSG00000022799
KO:
mmu:12549
|
| Nucleutide sequences |
EMBL-CDS:
AAD38043.1,
BAE38872.1,
BAE38901.1,
BAC98119.1,
BAE29314.1,
BAE33406.1,
BAE29205.1,
BAE23651.1,
AAI38871.1
Ensembl_TRS:
ENSMUST00000023487
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023487
RefSeq:
NP_064656.2
|
| Others |
UniRef100:
UniRef100_A6X8Z5
UniRef90:
UniRef90_A6X8Z5
UniRef50:
UniRef50_Q2M1Z3
UniGene:
Mm.370848
CCDS:
CCDS28172.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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