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1254388 avrA

1254388

avrA

putative inner membrane protein

protein-coding

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

基因描述

Type Description
Definition putative inner membrane protein

研究结论

Date Results Publications
2018-03-17 12:10:00 Infection with bacterial AvrA-expressing Salmonella activates the pathway, which induces the beta-catenin signals and enhances colonic tumorigenesis. (Review) 28223148
2012-06-02 11:08:00 Salmonella AvrA modulates survival of infected macrophages likely via JNK suppression, and prevents macrophage death and rapid bacterial dissemination. 21899703
2011-04-23 10:04:00 At the early stage of Salmonella infection, AvrA mainly targeted pathways related to nuclear receptor signaling and oxidative phosphorylation. At the late stage of Salmonella infection, AvrA is associated with interferon-gamma responses. 21182782
2010-05-10 12:12:00 Cells infected with AvrA-sufficient Salmonella have increased p53 acetylation, whereas cells infected with AvrA-deficient Salmonella have less p53 acetylation. AvrA expression increased p53 transcriptional activity and induced cell cycle arrest. 20224008
2010-01-21 13:04:00 Results show that AvrA (an effector protein of this TTSS) specifically inhibits the Salmonella-induced activation of the JNK pathway thru MKK7, but it does not interfere with the bacterial infection-induced NF-kappaB activation. 19779561

名称对应

Type IDs
Gene
UniProtKB-ID: Q8ZMI3_SALTY
UniprotKB: Q8ZMI3
UniParc: UPI00000CD318
EMBL: AE006468
EnsemblGenome: STM2865
KO: stm:STM2865
Nucleutide sequences
EMBL-CDS: AAL21745.1
Protein sequencees
RefSeq: NP_461786.1
Others
UniRef100: UniRef100_A0A719ERC4
UniRef90: UniRef90_A0A5I4IE63
UniRef50: UniRef50_O68718

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研究热度

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