| Type | Description |
|---|---|
| Definition | cell division cycle 37 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-28 10:48:00 | Results showed that Cdc37 acts as a bridge to direct Hsp90 to the transcription factor viral P proteins of all lyssaviruses. Although Cdc37 can load P proteins onto Hsp90, with or without binding to Hsp90, the interaction between Cdc37 and Hsp90 appears to provide additional allosterical regulation of its chaperone activity. Notably, both phosphorylated and non-P Cdc37 could facilitate Hsp90-mediated protein maturation. | 27251758 |
| 2017-08-19 11:52:00 | Niclosamide ethanolamine disrupted the interaction between cell division cycle 37 and heat shock protein 90 in hepatocellular carcinoma, reducing tumor growth. | 28284560 |
| 2012-10-27 10:12:00 | A series of tyrosine phosphorylation events, involving both p50(Cdc37) and Hsp90, are minimally sufficient to provide directionality to the chaperone cycle. | 22727666 |
| 2010-05-31 11:24:00 | Hsp90-Cdc37 complex acta as an endogenous regulator of noncanonical p38alpha activity. | 20299663 |
| 2010-01-21 00:00:00 | CDC37 binds to Akt and HSP90 in the signal transduction pathway in human tumor cells | 12176997 |
| Type | IDs |
|---|---|
| Synonymous | p50, p50Cdc37 |
| Gene |
UniProtKB-ID:
CDC37_MOUSE
UniprotKB:
Q61081
UniParc:
UPI0000027D08
EMBL:
AK145671,
BC060079,
AK168651,
AK010494,
U43076,
AK013255
Ensembl:
ENSMUSG00000019471
KO:
mmu:12539
|
| Nucleutide sequences |
EMBL-CDS:
BAE40508.1,
BAB26984.1,
AAB18761.1,
AAH60079.1,
BAE26580.1,
BAB28749.1
Ensembl_TRS:
ENSMUST00000019615
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019615
RefSeq:
NP_001365725.1,
NP_058022.1
|
| Others |
UniRef100:
UniRef100_Q61081
UniRef90:
UniRef90_Q61081
UniRef50:
UniRef50_Q16543
UniGene:
Mm.32331
CCDS:
CCDS22894.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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