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1253270 hns

1253270

hns

transcriptional regulator

protein-coding

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

基因描述

Type Description
Definition transcriptional regulator

研究结论

Date Results Publications
2020-07-25 12:10:00 Facultative intracellular pathogen Salmonella enterica serovar Typhimurium decreases H-NS amounts 16-fold when inside macrophages. This decrease requires both the protease Lon and the DNA-binding virulence regulator PhoP. The decrease in H-NS abundance reduces H-NS binding to foreign DNA, allowing transcription of foreign genes, including those required for intramacrophage survival. 32209674
2019-12-14 10:27:00 These data support two mechanisms adapted for the expression of ssrAB under different growth conditions. One involves the additive action of SlyA and HilD, whereas the other involves SlyA, but not HilD, to counteract H-NS-mediated repression on ssrAB, thus favoring in both cases the activation of ssrAB by OmpR. 30718301
2011-01-29 11:27:00 In conclusion, Fur activates hilA by repressing the expression of hns. 21075923
2011-01-15 10:20:00 Data suggest that Sfh acts as a molecular backup for H-NS and that it provides its 'stealth' function by replacing H-NS on the chromosome, thus minimizing disturbances to the H-NS-DNA binding pattern in cells that acquire pSfR27. 20444106
2010-01-21 00:00:00 As Hha and YdgT interact with H-NS, our findings strongly suggest that Hha and/or YdgT must form complexes with H-NS when they silence these DNA regions. 18039769

名称对应

Type IDs
Gene
UniProtKB-ID: HNS_SALTY
UniprotKB: P0A1S2
UniParc: UPI0000059F60
EMBL: M37891, X14375, AE006468
EnsemblGenome: STM1751
KO: stm:STM1751
Nucleutide sequences
EMBL-CDS: CAA32549.1, AAB61148.1, AAL20669.1
EnsemblGenome_TRS: AAL20669
Protein sequencees
EnsemblGenome_PRO: AAL20669
RefSeq: NP_460710.1
Others
UniRef100: UniRef100_A0A0F6B244
UniRef90: UniRef90_A0A0F6B244
UniRef50: UniRef50_A0A0F6B244

全选

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