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1252748 phoQ

1252748

phoQ

sensor protein PhoQ

protein-coding

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

基因描述

Type Description
Definition sensor protein PhoQ

研究结论

Date Results Publications
2018-06-02 10:54:00 These data suggest that when Salmonella experiences mildly acidic pH, the virulence regulator PhoP activation requires the sensor protein PhoQ to detect pH and the Salmonella-specific protein UgtL to amplify the PhoQ response. 28851823
2016-03-12 11:41:00 Salmonella enterica Typhimurium, bearing the acidic pH and divalent cation unresponsive phoQ(W104C-A128C) allele is virulent in mice, indicating that acidic pH and divalent cation sensing by PhoQ are dispensable for virulence. 26002083
2016-01-16 11:43:00 Changes in the periplasmic domain of PhoQ lead to conformational movements in the HAMP domain helices which disrupt interaction between the HAMP and the catalytic domains, thus promoting increased kinase activity. 26015499
2014-11-22 13:40:00 study describes a mechanism whereby the transcriptional activator PhoP elicits expression of dissimilar gene sets when its cognate sensor PhoQ is activated by different signals in the periplasm 24256574
2013-12-14 12:10:00 These data demonstrated that Salmonella Typhimurium PhoQ can sense cationic antimicrobial peptides and CRAMP serves as a putative direct PhoPQ activation signal in the mouse intestine. 22919691

名称对应

Type IDs
Gene
UniProtKB-ID: PHOQ_SALTY
UniprotKB: P0DM80
UniParc: UPI00001319CB
EMBL: AE006468, M24424
EnsemblGenome: STM1230
KO: stm:STM1230
Nucleutide sequences
EMBL-CDS: AAA27189.1, AAL20159.1
EnsemblGenome_TRS: AAL20159
Protein sequencees
EnsemblGenome_PRO: AAL20159
RefSeq: NP_460200.1
Others
UniRef100: UniRef100_Q57QC4
UniRef90: UniRef90_Q8Z7H3
UniRef50: UniRef50_Q8Z7H3

全选

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研究热度

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