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1252609 sopB

1252609

sopB

inositol phosphatase

protein-coding

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

基因描述

Type Description
Definition inositol phosphatase

研究结论

Date Results Publications
2017-05-27 11:07:00 These findings show that SopB suppresses host cell apoptosis by binding to TRAF6 and preventing mitochondrial reactive oxygen species generation. 27473656
2016-12-31 10:48:00 This work reveals the unique ability of bacterial effector protein SopB to utilize both its 4- and 5-phosphatase activities to regulate phosphoinositide dynamics to promote bacterial entry 26537021
2015-05-16 10:05:00 SopB secretion was also considerably impaired in the absence of dam. 24947562
2014-02-22 10:44:00 The structural organization of the N-terminus domain of SopB, a virulence factor of Salmonella, depends on the nature of its protein partners 24075929
2011-11-19 10:59:00 Data found that SopB-dependent membrane translocation and phosphorylation of Akt are insensitive to the PI3K inhibitor wortmannin. 21779406

名称对应

Type IDs
Gene
UniProtKB-ID: SOPB_SALTY
UniprotKB: O30916
UniParc: UPI00000CCFE8
EMBL: AF213335, AE006468, AF021817
EnsemblGenome: STM1091
KO: stm:STM1091
Nucleutide sequences
EMBL-CDS: AAC46234.1, AAL20023.1, AAF21057.2
EnsemblGenome_TRS: AAL20023
Protein sequencees
EnsemblGenome_PRO: AAL20023
RefSeq: NP_460064.1
Others
UniRef100: UniRef100_O30916
UniRef90: UniRef90_O30916
UniRef50: UniRef50_O30916

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Yale University School of Medicine

3
2

University of British Columbia

2
3

Sidney Kimmel Cancer Center, 10835 Altman Row, San Diego, California 92121, USA. mmcclelland@skcc.org

1
4

Cell Biology Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

1
5

Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA. lknodler@niaid.nih.gov

1
热点人员
排名 研究人员 文献
1

B Brett Finlay

5
2

Jorge E Galán

3
3

Olivia Steele-Mortimer

3
4

Leigh A Knodler

3
5

Karsten Hueffer

2
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