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12526 Cd8b1

12526

Cd8b1

CD8 antigen, beta chain 1

protein-coding

Mus musculus

基因描述

Type Description
Definition CD8 antigen, beta chain 1

研究结论

Date Results Publications
2021-03-13 13:15:00 Constitutive CD8 expression drives innate CD8(+) T-cell differentiation via induction of iNKT2 cells. 31980555
2015-10-17 11:29:00 Lck-CD8 interaction is required for initial CD8 recruitment. 25427562
2015-06-20 12:09:00 Comparing the sequences of mouse, human, rat and dog Cd8a and Cd8b1 gene loci identified 10 evolutionarily conserved regions (ECR). 6 ECRs overlapped with previously identified Cd8 enhancers. ECR-4 recruits transcription factors to the Cd8ab gene complex. 25548254
2014-03-29 11:15:00 CREMalpha orchestrates epigenetic remodeling of the CD8A,B through the recruitment of DNA methyltransferase (DNMT) 3a and histone methyltransferase G9a. 24297179
2013-09-14 11:42:00 We propose that ADP-ribosylation of CD8-beta can regulate the coreceptor function of CD8 in the presence of elevated levels of extracellular NAD(+) . 23575529

名称对应

Type IDs
Synonymous Cd8b, Ly-3, Ly-C, Lyt-3
Gene
UniProtKB-ID: CD8B_MOUSE, Q3TEK8_MOUSE
UniprotKB: P10300, Q3TEK8
UniParc: UPI0000027355
EMBL: M22070, M17534, X07698, M16799, M26442, M22065, M26444, M26443, M19504, M26441, M22068, M26446, U34882, M22069, X07997, M26445, M22067, AK169581, M22066
Ensembl: ENSMUSG00000053044
KO: mmu:12526
Nucleutide sequences
EMBL-CDS: AAA92534.1, AAA39454.1, CAA30803.1, AAA39455.1, AAA39480.1, CAA30537.1, AAA39479.1, AAA39456.1, BAE41240.1
Ensembl_TRS: ENSMUST00000065248
Protein sequencees
Ensembl_PRO: ENSMUSP00000070131
RefSeq: NP_033988.1
Others
UniRef100: UniRef100_P10300
UniRef90: UniRef90_P10300
UniRef50: UniRef50_P10300
UniGene: Mm.333148
CCDS: CCDS39506.1

全选

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