| Type | Description |
|---|---|
| Definition | CD86 antigen |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:26:00 | Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. | 32572241 |
| 2020-06-06 11:13:00 | CD86 is targeted by miR-199a-3p, thereby linking it to DC maturation. miR-199a-3p therefore directly inhibits CD86 expression via 3'-UTR targeting, subsequently prolonging allograft survival in a mouse heart transplantation model. miR-199a-3p over-expression may therefore be a potential therapeutic strategy for use in organ transplantation or patients with autoimmune diseases. | 31448543 |
| 2019-08-10 12:19:00 | Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells | 30010888 |
| 2019-06-23 15:02:00 | CD80/CD86 signaling plays a significant role in the initial inflammatory response to S. aureus. | 29402722 |
| 2018-02-03 11:45:00 | Our results reveal a role for B7-2 as obligatory receptor for superantigens. B7-2 homodimer interface mimotopes prevent superantigen lethality by blocking the superantigen-host costimulatory receptor interaction. | 27708164 |
| Type | IDs |
|---|---|
| Synonymous | B7, B7-2, B7.2, B70, CLS1, Cd28l2, ETC-1, Ly-58, Ly58, MB7, MB7-2, TS/A-2 |
| Gene |
UniProtKB-ID:
CD86_MOUSE,
Q61238_MOUSE,
Q549Q9_MOUSE
UniprotKB:
P42082,
Q61238,
Q549Q9
UniParc:
UPI000000019B,
UPI0000038AD0,
UPI00000E6B17
EMBL:
AH006741,
U39466,
U39460,
U39459,
U39456,
U39464,
AF065899,
U39462,
AF065898,
U39463,
U39461,
U39465,
AF065900,
AK079513,
L25606,
S70108,
AF065897
Ensembl:
ENSMUSG00000022901
KO:
mmu:12524
|
| Nucleutide sequences |
EMBL-CDS:
AAB30744.2,
AAC52336.1,
AAA79770.1,
AAC52334.1,
AAC52335.1,
BAC37666.1,
AAD25882.1,
AAD25881.1,
AAD25883.1,
AAD25880.1
Ensembl_TRS:
ENSMUST00000089620
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087047
RefSeq:
NP_062261.3,
XP_006521804.1,
XP_011244114.1
|
| Others |
UniRef100:
UniRef100_Q61238,
UniRef100_P42082
UniRef90:
UniRef90_P42082
UniRef50:
UniRef50_P42082
UniGene:
Mm.1452
CCDS:
CCDS28155.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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