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12518 Cd79a

12518

Cd79a

CD79A antigen (immunoglobulin-associated alpha)

protein-coding

Mus musculus

基因描述

Type Description
Definition CD79A antigen (immunoglobulin-associated alpha)

研究结论

Date Results Publications
2014-08-23 11:17:00 BCR activation is accompanied by asymmetric conformational changes, possibly promoting the binding of Igalpha and Igbeta to differently localized signaling complexes 24244439
2014-07-26 11:19:00 CD79a myeloid cells showed enhanced ability to promote primary tumor growth and metastasis. 24146823
2014-06-07 10:06:00 Data indicate that in the absence of DGKzeta, the threshold for B cell antigen receptor (BCR) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK) pathway, was markedly reduced in mature follicular B cells. 24129701
2013-05-18 11:32:00 Data show that the B cell antigen receptor (BCR) and Igalpha may be required for B cell survival because they function as adaptor proteins in a BAFFR signaling pathway leading to activation of Syk, indicating crosstalk between the two receptors. 23453634
2012-05-26 11:31:00 The mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection. 21688146

名称对应

Type IDs
Synonymous Ig-alpha, Iga, Igalpha, Ly-54, Ly54, mb-1
Gene
UniProtKB-ID: CD79A_MOUSE
UniprotKB: P11911
UniParc: UPI000011C5CA
EMBL: S59359, M31773, BC027633, X13450
Ensembl: ENSMUSG00000003379
KO: mmu:12518
Nucleutide sequences
EMBL-CDS: AAH27633.1, AAA39494.1, CAA31801.1
Ensembl_TRS: ENSMUST00000003469
Protein sequencees
Ensembl_PRO: ENSMUSP00000003469
RefSeq: NP_031681.2
Others
UniRef100: UniRef100_P11911
UniRef90: UniRef90_P11911
UniRef50: UniRef50_P11911
UniGene: Mm.1355
CCDS: CCDS20967.1

全选

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研究热度

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