| Type | Description |
|---|---|
| Definition | mitochondrial elongation factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | Mitochondrial fragmentation enables localized signaling required for cell repair. | 32236517 |
| 2021-01-23 13:01:00 | An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications. | 32068312 |
| 2019-10-05 10:37:00 | In health, MiD49 regulate Drp1-mediated fission, whereas in disease, epigenetic upregulation of MiD49 increases mitotic fission, which drives pathological proliferation and apoptosis resistance | 29431643 |
| 2018-12-22 11:21:00 | cryo-electron microscopy structure of full-length human DRP1 co-assembled with MID49 and an analysis of structure- and disease-based mutations | 29899447 |
| 2017-12-16 12:25:00 | Knockdown of MIEF2 reduces DOX-induced mitochondrial fission and apoptosis in cardiomyocytes and in vivo. Also, knockdown of MIEF2 protects heart from DOX-induced cardiotoxicity. Our study identifies a novel pathway composed of Foxo3a and MIEF2 that mediates DOX cardiotoxicity. | 28137654 |
| Type | IDs |
|---|---|
| Synonymous | MID49, SMCR7 |
| Gene |
UniProtKB-ID:
MID49_HUMAN
UniprotKB:
Q96C03
UniParc:
UPI00001C0FB1,
UPI00005A76FC,
UPI0000071A1E
EMBL:
CH471196,
AK128310,
AC127537,
BC014973,
AK056165,
AF467443
Ensembl:
ENSG00000284495,
ENSG00000177427
KO:
hsa:125170
|
| Nucleutide sequences |
EMBL-CDS:
BAB71108.1,
AAH14973.1,
AAL78340.1,
BAC87377.1,
EAW55652.1,
EAW55651.1
Ensembl_TRS:
ENST00000323019,
ENST00000395706,
ENST00000395704,
ENST00000640122,
ENST00000640339,
ENST00000640637
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000323591,
ENSP00000490984,
ENSP00000379056,
ENSP00000379057,
ENSP00000491181,
ENSP00000492195
RefSeq:
NP_631901.2,
XP_016879679.1,
NP_001138372.1,
NP_683684.2
|
| Others |
UniRef100:
UniRef100_Q96C03
UniRef90:
UniRef90_Q96C03
UniRef50:
UniRef50_Q96C03
UniGene:
Hs.655555
CCDS:
CCDS45624.1,
CCDS11193.1,
CCDS45625.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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