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12509 Cd59a

12509

Cd59a

CD59a antigen

protein-coding

Mus musculus

基因描述

Type Description
Definition CD59a antigen

研究结论

Date Results Publications
2018-03-03 11:15:00 Data (including data from studies using knockout mice) suggest that CD59a, CD59b, and ApoE are involved in development of diabetes-induced atherosclerosis; here, deficiency of CD59a/CD59b (in ApoE deficient mice) accelerates development of atherosclerosis in mice with type 1 diabetes. (CD59a = CD59a antigen; CD59b = CD59b antigen; ApoE = apolipoprotein E) 27729184
2016-08-13 11:53:00 Varicella-zoster virus infection upregulates host CD59 expression in a tissue-specific manner. 26891237
2016-04-30 10:22:00 This study support a role of Cd59a in controlling the innate immune status of the RPE-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging 26234657
2015-07-25 10:28:00 results implicate CD59 as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology. 24698947
2014-07-26 10:33:00 Soluble forms of CD59 (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration. 24664728

名称对应

Type IDs
Synonymous AA987121, Cd59, protectin
Gene
UniProtKB-ID: CD59A_MOUSE, A2BI31_MOUSE
UniprotKB: O55186, A2BI31
UniParc: UPI0000004148
EMBL: U60473, AF247652, AK018136, BC132089, AK002743, AK005507, AK080728, BC132115
Ensembl: ENSMUSG00000032679
KO: mmu:12509
Nucleutide sequences
EMBL-CDS: BAC37996.1, AAG15314.1, BAB24087.1, BAB22321.1, AAC00055.1, BAB31088.1, AAI32116.1, AAI32090.1
Ensembl_TRS: ENSMUST00000040423, ENSMUST00000168176
Protein sequencees
Ensembl_PRO: ENSMUSP00000048041, ENSMUSP00000132774
RefSeq: XP_030102896.1, NP_001104530.1, XP_006498714.1, XP_006498713.1, XP_036013755.1, NP_031678.1
Others
UniRef100: UniRef100_O55186
UniRef90: UniRef90_O55186
UniRef50: UniRef50_P27274
UniGene: Mm.247265
CCDS: CCDS16487.1

全选

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