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125050 RN7SK

125050

RN7SK

RNA, 7SK small nuclear

snRNA

Homo sapiens

基因描述

Type Description
Definition RNA, 7SK small nuclear

研究结论

Date Results Publications
2020-12-19 13:42:00 Analysis of RNA binding properties of human Ku protein reveals its interactions with 7SK snRNA and protein components of 7SK snRNP complex. 32105815
2020-05-30 11:27:00 Our results demonstrated the transient knockdown of Rn7SK in mesenchymal stem cells leads to delayed senescence, while its overexpressions shows opposite effects. 30637716
2018-11-10 12:03:00 The 7SK small nuclear RNA is a multifunctional transcriptional regulatory RNA that controls the nuclear activity of the positive transcription elongation factor b (P-TEFb), specifically targets P-TEFb to the promoter regions of selected protein-coding genes and promotes transcription of RNA polymerase II-specific spliceosomal small nuclear RNA genes. 28820318
2018-02-10 10:03:00 These findings identify a novel role for HIV-1 TAR in the absence of Tat, involving the interference with host cellular immune responses by targeting 7SK RNA-mediated gene expression and P-TEFb inactivation. 29037489
2017-07-01 11:47:00 The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, also functions as a canonical transcription factor that, in collaboration with the little elongation complex (LEC) comprising ELL, Ice1, Ice2, and ZC3H8, promotes transcription of RNAPII-specific spliceosomal snRNA and small nucleolar RNA (snoRNA) genes. 28254838

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Type IDs
Synonymous 7SK