| Type | Description |
|---|---|
| Definition | CD3 antigen, epsilon polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 10:53:00 | The data show that CD3epsilon chain couples to Cbl via simultaneous binding of both proteins to Numb, thus mediating TCR degradation | 26507128 |
| 2015-12-19 12:04:00 | IL-17-producing CD3(bright) gammadelta T cells responded promptly and strongly to pneumococcal infection and during skin inflammation. | 25385067 |
| 2015-02-21 11:41:00 | these results suggest that CD3zeta can be degraded by two pathways: SLAP/c-Cbl, which targets internalized cell surface CD3zeta dependent on TCR signaling, and LAPTM5, which targets intracellular CD3zeta independent of TCR signaling. | 24638062 |
| 2014-08-23 10:12:00 | these results indicate that membrane association of the CD3epsilon signaling domain is required for optimal thymocyte development and peripheral T cell function. | 24899501 |
| 2014-07-26 11:57:00 | These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT and PLCgamma1 in Dow2-induced anergic T cells. The novel CD3-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression | 24595757 |
| Type | IDs |
|---|---|
| Synonymous | AI504783, CD3, CD3epsilon, T3e |
| Gene |
UniProtKB-ID:
CD3E_MOUSE,
A6H6M1_MOUSE
UniprotKB:
P22646,
A6H6M1
UniParc:
UPI0000029761
EMBL:
BC145926,
M23370,
M23373,
M23374,
J02990,
M23372,
BC145954,
M23376,
M23375,
GU456631,
M23371
Ensembl:
ENSMUSG00000032093
KO:
mmu:12501
|
| Nucleutide sequences |
EMBL-CDS:
AAA40296.1,
AAA72720.1,
ADD13994.1,
AAI45955.1,
AAI45927.1
Ensembl_TRS:
ENSMUST00000102832
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099896
RefSeq:
XP_006510029.1,
NP_031674.1
|
| Others |
UniRef100:
UniRef100_P22646
UniRef90:
UniRef90_P22646
UniRef50:
UniRef50_P22646
UniGene:
Mm.210361
CCDS:
CCDS23125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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