| Type | Description |
|---|---|
| Definition | sphingolipid transporter 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:46:00 | SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway. | 31206801 |
| 2020-06-27 11:09:00 | A possible contribution of the SPNS2 variation to POI was not strictly ruled out, but various data presented in the text including reported association of variations in related gene ALOX12 with menopause-age and role of ALOX12B in atretic bovine follicle formation argue in favor of ALOX12B. It is, therefore, concluded that the mutation in ALOX12B is the likely cause of POI in the pedigree. | 32253496 |
| 2019-05-04 12:46:00 | Spinster 2 (SPNS2) was shown to act as a mediator of intracellular sphingosine-1-phosphate (S1P) release and play an important role in the regulation of S1P [Review]. | 30196234 |
| 2018-09-29 10:32:00 | our data demonstrate that Spns2 and S1P have a crucial effect on proximal tubular epithelial cells by regulating an inflammatory process and a subsequent fibrotic reaction, and also by influencing other tubular transporters that are involved in the pathophysiology of inflammatory and fibrotic kidney diseases. | 29772789 |
| 2018-05-19 10:53:00 | Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development | 27562371 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SPNS2_HUMAN
UniprotKB:
Q8IVW8
UniParc:
UPI00001C1FCB
EMBL:
BC041772,
AB441165
Ensembl:
ENSG00000183018
KO:
hsa:124976
|
| Nucleutide sequences |
EMBL-CDS:
AAH41772.2,
BAH15192.1
Ensembl_TRS:
ENST00000329078
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333292
RefSeq:
NP_001118230.1,
XP_024306342.1
|
| Others |
UniRef100:
UniRef100_Q8IVW8
UniRef90:
UniRef90_Q91VM4
UniRef50:
UniRef50_Q91VM4
UniGene:
Hs.22824
CCDS:
CCDS42237.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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