| Type | Description |
|---|---|
| Definition | scavenger receptor class B, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:02:00 | New observations from this study include altered expression of Pcp2 and Limp2 in Npc1 mutant mice relative to control, with Pcp2 exhibiting multiple isoforms and specific to the cerebella. This study provides valuable insight into pathways altered in the late-stage pathophysiology of NPC1 | 30888112 |
| 2019-12-14 10:09:00 | Study provides multiple lines of evidence that LIMP-2 participates in lipid transport from lysosomes by transporting cholesterol (and possibly also other lipid species) through its luminal cavity to the lysosomal membrane and later to lipid droplets. Data indicate that LIMP-2 operates in parallel with Niemann Pick (NPC)-proteins, mediating a slower mode of lysosomal cholesterol export. | 31387993 |
| 2018-10-06 11:59:00 | LIMP-2 facilitates transport of phospholipids into murine fibroblasts, with a strong substrate preference for phosphatidylserine. | 29199275 |
| 2017-04-29 11:05:00 | The findings identify SR-BII as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK-mediated signaling pathways. | 28423002 |
| 2016-10-08 12:00:00 | AP-3-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 in vitro and in vivo | 26907692 |
| Type | IDs |
|---|---|
| Synonymous | 9330185J12Rik, Cd36l2, LGP85, LIMP II, LIMP-2, MLGP85 |
| Gene |
UniProtKB-ID:
SCRB2_MOUSE
UniprotKB:
O35114
UniParc:
UPI00000231D6
EMBL:
AK083038,
AK011123,
AK144235,
BC029073,
AB008553
Ensembl:
ENSMUSG00000029426
KO:
mmu:12492
|
| Nucleutide sequences |
EMBL-CDS:
AAH29073.1,
BAA23372.1,
BAB27416.1,
BAC38740.1,
BAE25789.1
Ensembl_TRS:
ENSMUST00000031377
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031377
RefSeq:
NP_031670.1
|
| Others |
UniRef100:
UniRef100_O35114
UniRef90:
UniRef90_O35114
UniRef50:
UniRef50_Q14108
UniGene:
Mm.297964
CCDS:
CCDS19431.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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