| Type | Description |
|---|---|
| Definition | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 11:02:00 | In this review, we summarize current knowledge about the WFIKKN proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB proteins to their respective receptors, thus regulating the balance between the activation of Smad and non-Smad pathways by TGFB. | 27325460 |
| 2017-03-22 10:11:00 | WFIKKN2 expression is significantly downregulated in human masticatory mucosa during wound healing | 28005267 |
| 2013-10-26 14:05:00 | Data suggest that myostatin binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 but not WFIKKN2; various forms of myostatin (promyostatin, myostatin pro-domain, and latent/processed myostatin) bind WFIKKN1 but not WFIKKN2. | 23829672 |
| 2012-09-15 10:10:00 | After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of GASP-1 while postmenopausal women using HT showed a significant increased expression over controls. | 22395277 |
| 2011-01-15 10:49:00 | data indicate that WFIKKN proteins are antagonists of GDF8 and GDF11, but in the case of TGFbeta1, BMP2 and BMP4 they function as growth factor binding proteins | 21054789 |
| Type | IDs |
|---|---|
| Synonymous | GASP-1, WFDC20B, WFIKKNRP, hGASP-1 |
| Gene |
UniProtKB-ID:
WFKN2_HUMAN,
C9J6G4_HUMAN
UniprotKB:
Q8TEU8,
C9J6G4
UniParc:
UPI0001914DC1,
UPI000004139B
EMBL:
AY358142,
AF468657,
AC091062
Ensembl:
ENSG00000173714
KO:
hsa:124857
|
| Nucleutide sequences |
EMBL-CDS:
AAL77058.1,
AAQ88509.1
Gene_ORFName:
UNQ9235/PRO31996
Ensembl_TRS:
ENST00000311378,
ENST00000426127
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311184,
ENSP00000405889
RefSeq:
NP_783165.1,
NP_001317270.1
|
| Others |
UniRef100:
UniRef100_Q8TEU8
UniRef90:
UniRef90_Q7TQN3
UniRef50:
UniRef50_Q7TQN3
UniGene:
Hs.211475
CCDS:
CCDS11575.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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