Ctla4 - cytotoxic T-lymphocyte-associated protein 4-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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12477 Ctla4

基因描述

Type	Description
Definition	cytotoxic T-lymphocyte-associated protein 4

研究结论

Date	Results	Publications
2021-04-17 13:17:00	Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice.	32872393
2021-02-13 13:27:00	CTLA-4 expression by B-1a B cells is essential for immune tolerance.	33483505
2020-10-24 13:54:00	CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice.	31147569
2020-08-29 12:47:00	Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.	31466995
2020-07-04 11:47:00	We could demonstrate that an early preventive administration of CTLA-4-Ig suppresses effector T cell function and therefore ameliorates liver fibrosis. CTLA-4-Ig administration after onset of egg production fails to treat hepatic fibrosis	31950032

名称对应

Type	IDs
Synonymous	Cd152, Ctla-4, Ly-56
Gene	UniProtKB-ID: CTLA4_MOUSE, Q5SSM0_MOUSE, Q6GTR6_MOUSE UniprotKB: P09793, Q5SSM0, Q6GTR6 UniParc: UPI00001ED2E4, UPI000002738A, UPI000000B2A4 EMBL: AL663047, GQ420692, AL646054, M74362, CR936839, BC042741, GQ420693, AF142145, X05719 Ensembl: ENSMUSG00000026011 KO: mmu:12477
Nucleutide sequences	EMBL-CDS: CAA29191.1, AAA37489.1, AAF01489.1, CAM13244.1, ACX50465.1, ACX50466.1, AAH42741.1, CAM13245.1 Gene_ORFName: CH29-120A16.2-002, CH29-120A16.2-001 Ensembl_TRS: ENSMUST00000097720, ENSMUST00000027164
Protein sequencees	Ensembl_PRO: ENSMUSP00000095327, ENSMUSP00000027164 RefSeq: NP_033973.2, XP_036012250.1, NP_001268905.1
Others	UniRef100: UniRef100_P09793, UniRef100_Q5SSM0, UniRef100_Q6GTR6 UniRef90: UniRef90_P09793, UniRef90_Q5SSM0 UniRef50: UniRef50_P16410, UniRef50_G3V7D2 UniGene: Mm.390 CCDS: CCDS14993.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
33483505	CTLA-4 expression by B-1a B cells is essential for immune tolerance. Nat Commun Yang Yang , Xiao Li , Zhihai Ma , Chunlin Wang , Qunying Yang , Miranda Byrne-Steele , Rongjian Hong , Qing Min , Gao Zhou , Yong Cheng , Guang Qin , Justin V Youngyunpipatkul , James B Wing , Shimon Sakaguchi , Christian Toonstra , Lai-Xi Wang , Jose G Vilches-Moure , Denong Wang , Michael P Snyder , Ji-Yang Wang , Jian Han , Leonore A Herzenberg	2021-01-22	-
32872393	Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice. Cells Kikkie Poels , Mandy M T van Leent , Myrthe E Reiche , Pascal J H Kusters , Stephan Huveneers , Menno P J de Winther , Willem J M Mulder , Esther Lutgens , Tom T P Seijkens	2020-08-29	-
31676858	TIM3 comes of age as an inhibitory receptor. Nat Rev Immunol Yochai Wolf , Ana C Anderson , Vijay K Kuchroo	2020-03-01	-
32049052	Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity Simon Zenke , Margriet M Palm , Julia Braun , Alina Gavrilov , Philippa Meiser , Jan P BÃ¶ttcher , Niklas Beyersdorf , Stephan Ehl , Audrey Gerard , Tim LÃ¤mmermann , Ton N Schumacher , Joost B Beltman , Jan C Rohr	2020-02-18	-
31466995	Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner. Cancer Immunol Res Lewis Zhichang Shi , Sangeeta Goswami , Tihui Fu , Baoxiang Guan , Jianfeng Chen , Liangwen Xiong , Jan Zhang , Derek Ng Tang , Xuejun Zhang , Luis Vence , Jorge Blando , James P Allison , Renata Collazo , Jianjun Gao , Padmanee Sharma	2019-11-01	-
31288148	Deficiency of programmed cell death 4 affects the balance of T cell subsets in hyperlipidemic mice. Mol. Immunol. Yang Jiang , Qi Gao , Li-Yang Wang , Tian Ma , Fa-Liang Zhu , Qun Wang , Fei Gao , Chun Guo , Li-Ning Zhang	2019-08-01	-
31152091	CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells. Sci Immunol Vitalijs Ovcinnikovs , Ellen M Ross , Lina Petersone , Natalie M Edner , Frank Heuts , Elisavet Ntavli , Alexandros Kogimtzis , Alan Kennedy , Chun Jing Wang , Clare L Bennett , David M Sansom , Lucy S K Walker	2019-05-31	-
31147569	CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice. Sci Rep Hilman Zulkifli Amin , Naoto Sasaki , Tomoya Yamashita , Taiji Mizoguchi , Tomohiro Hayashi , Takuo Emoto , Takuya Matsumoto , Naofumi Yoshida , Tokiko Tabata , Sayo Horibe , Shoji Kawauchi , Yoshiyuki Rikitake , Ken-Ichi Hirata	2019-05-30	-
30910862	Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells. J. Immunol. Priscilla Do , Kyle A Beckwith , Carolyn Cheney , Minh Tran , Larry Beaver , Brittany G Griffin , Xiaokui Mo , Yang Liu , Rosa Lapalombella , Erin Hertlein , Natarajan Muthusamy , John C Byrd	2019-05-01	-
30643268	Regulatory T cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells. Nat. Immunol. Billur Akkaya , Yoshihiro Oya , Munir Akkaya , Jafar Al Souz , Amanda H Holstein , Olena Kamenyeva , Juraj Kabat , Ryutaro Matsumura , David W Dorward , Deborah D Glass , Ethan M Shevach	2019-02-01	-

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