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12457 Noct

12457

Noct

nocturnin

protein-coding

Mus musculus

基因描述

Type Description
Definition nocturnin

研究结论

Date Results Publications
2020-04-18 11:43:00 The Noct gene encodes a protein (NOC) that is highly conserved with the endonuclease/exonuclease/phosphatase (EEP) domain-containing CCR4 family of deadenylases, but highly purified NOC possesses little or no ribonuclease activity. NOC utilizes the dinucleotide NADP(H) as a substrate, removing the 2' phosphate to generate NAD(H), and is a direct regulator of oxidative stress response through its NADPH 2' phosphatase activ 31879354
2019-06-01 10:17:00 posttranscriptional control by Nocturnin regulates the amplitude of critical metabolic pathways, and loss of this activity results in increased metabolic flux and reduced obesity 29386110
2016-10-22 11:34:00 Data suggest that Nocturnin (NOC) exerts strong effects on physiology through direct and indirect control of target mRNAs. 26586468
2014-02-15 12:12:00 precise expression of nocturnin is critical to proper development of early mouse embryos 23449310
2012-04-07 10:57:00 Nocturnin plays a role in linking nutrient sensing by the circadian clock to lipid mobilization in the adipocytes 21347334

名称对应

Type IDs
Synonymous AU043840, Ccr4, Ccrn4l
Gene
UniProtKB-ID: NOCT_MOUSE, B2RTJ8_MOUSE
UniprotKB: O35710, B2RTJ8
UniParc: UPI00001C2B7F, UPI0000004187
EMBL: BC139369, U70139, AF183960, AF199491, AK087790, BC139370
Ensembl: ENSMUSG00000023087
KO: mmu:12457
Nucleutide sequences
EMBL-CDS: AAD56547.1, AAG01384.1, BAC40004.1, AAB62717.1, AAI39371.1, AAI39370.1
Ensembl_TRS: ENSMUST00000144826, ENSMUST00000167780, ENSMUST00000023849
Protein sequencees
Ensembl_PRO: ENSMUSP00000023849, ENSMUSP00000141416, ENSMUSP00000130347
RefSeq: XP_006501019.1, NP_033964.1
Others
UniRef100: UniRef100_O35710
UniRef90: UniRef90_O35710
UniRef50: UniRef50_O35710
UniGene: Mm.86541
CCDS: CCDS17336.1

全选

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