| Type | Description |
|---|---|
| Definition | cyclin E1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:14:00 | Livers, but not other tissues of mice with inducible overexpression of cyclin E1, develop tumors. More hepatocytes from the cyclin E1-overexpressing mice were polyploid than from control mice, and had losses or gains of whole chromosomes, DNA damage, and oxidative stress. | 30878468 |
| 2019-06-15 12:28:00 | Study in a mouse endotoxemia model of inflammatory endothelial injury and human cells demonstrated that endothelial Sox17 expression plays an obligatory role in normalizing the endothelium. Restoration of endothelial integrity is mediated by activation of HIF-1alpha, upregulation of its target Sox17, and subsequent downstream expression of Cyclin E1 which mediates endothelial regeneration. | 31073164 |
| 2019-06-01 10:17:00 | SALL2 is a negative regulator of cell proliferation, an effect mediated in part by repression of G1-S cyclins' expression. | 29689621 |
| 2019-03-09 12:36:00 | High CCNE1 expression is associated with hepatitis and hepatocarcinogenesis. | 29551768 |
| 2018-10-06 10:24:00 | study suggests that hepatocellular carcinoma initiation specifically depends on CcnE1 and Cdk2, while HCC progression requires expression of any E-cyclin, but no Cdk2. | 30150405 |
| Type | IDs |
|---|---|
| Synonymous | AW538188, CycE1 |
| Gene |
UniProtKB-ID:
CCNE1_MOUSE
UniprotKB:
Q61457
UniParc:
UPI00001F4E27
EMBL:
BC106191,
BC084588,
BC062152,
X75888
Ensembl:
ENSMUSG00000002068
KO:
mmu:12447
|
| Nucleutide sequences |
EMBL-CDS:
AAH84588.1,
AAH62152.1,
AAI06192.1,
CAA53482.1
Ensembl_TRS:
ENSMUST00000108023
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103658
RefSeq:
NP_031659.2
|
| Others |
UniRef100:
UniRef100_Q61457
UniRef90:
UniRef90_P39949
UniRef50:
UniRef50_P39949
UniGene:
Mm.16110
CCDS:
CCDS39914.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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