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12428 Ccna2

12428

Ccna2

cyclin A2

protein-coding

Mus musculus

基因描述

Type Description
Definition cyclin A2

研究结论

Date Results Publications
2020-11-21 13:25:00 PDZRN3 protects against apoptosis in myoblasts by maintaining cyclin A2 expression. 31980707
2020-09-19 16:24:00 The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway. 30848072
2019-10-26 11:31:00 cyclin A2 functions in a noncanonical/non-cell cycle regulatory role to maintain adult pyramidal neuron ribostasis. 30579783
2017-11-18 13:33:00 We demonstrate that CCNA2-null progenitors suffer abnormal DNA repair, and implicate Cyclin A2 in double-strand break repair. Cyclin A2's DNA repair functions are conserved among cell lines, neural progenitors, and hippocampal neurons. We further demonstrate that neuronal CCNA2 ablation results in learning and memory deficits in aged mice. 27425845
2017-10-07 12:29:00 cyclin A2 mediates the fidelity ofmeiosis II by maintaining microtubule dynamics during the rapid formation of the meiosis II spindle. 28819014

名称对应

Type IDs
Synonymous AA408589, Ccn-1, Ccn1, Ccna, CycA2, Cyca
Gene
UniProtKB-ID: CCNA2_MOUSE
UniprotKB: P51943
UniParc: UPI0000022C9E
EMBL: BC052730, CH466530, AK044924, X75483, Z26580
Ensembl: ENSMUSG00000027715
KO: mmu:12428
Nucleutide sequences
EMBL-CDS: CAA53212.1, BAC32144.1, EDL35081.1, AAH52730.1, CAA81331.1
Ensembl_TRS: ENSMUST00000029270
Protein sequencees
Ensembl_PRO: ENSMUSP00000029270
RefSeq: NP_033958.2
Others
UniRef100: UniRef100_P51943
UniRef90: UniRef90_P51943
UniRef50: UniRef50_P20248
UniGene: Mm.4189
CCDS: CCDS17313.1

全选

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研究热度

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