GPR139 - G protein-coupled receptor 139-BMKCloudï½ç¾è¿å®¢äº

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124274 GPR139

基因描述

Type	Description
Definition	G protein-coupled receptor 139

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Molecular cloning of GPRg1, a Gq-coupled orphan receptor that is expressed in the brain.	15845401

名称对应

Type	IDs
Synonymous	GPRg1, PGR3
Gene	UniProtKB-ID: GP139_HUMAN, A0A142CHG1_HUMAN UniprotKB: Q6DWJ6, A0A142CHG1 UniParc: UPI000004C566 EMBL: BC137238, AY255545, CH471186, AY635179, KR081941, AK291384, AB083594, AB196529, BC137237 Ensembl: ENSG00000180269 KO: hsa:124274
Nucleutide sequences	EMBL-CDS: BAF84073.1, AAI37238.1, AAT65818.1, BAB89307.1, AAO85057.1, BAD97440.1, AAI37239.1, EAW50306.1, AMQ09597.1 Ensembl_TRS: ENST00000570682
Protein sequencees	Ensembl_PRO: ENSP00000458791 RefSeq: NP_001002911.1, NP_001305412.1
Others	UniRef100: UniRef100_Q6DWJ6 UniRef90: UniRef90_Q6DWJ6 UniRef50: UniRef50_Q80UC8 UniGene: Hs.446875 CCDS: CCDS32398.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26349500	GPR139, an Orphan Receptor Highly Enriched in the Habenula and Septum, Is Activated by the Essential Amino Acids L-Tryptophan and L-Phenylalanine. Mol. Pharmacol. Changlu Liu , Pascal Bonaventure , Grace Lee , Diane Nepomuceno , Chester Kuei , Jiejun Wu , Qingqin Li , Victory Joseph , Steven W Sutton , William Eckert , Xiang Yao , Lynn Yieh , Curt Dvorak , Nicholas Carruthers , Heather Coate , Sujin Yun , Christine Dugovic , Anthony Harrington , Timothy W Lovenberg	2015-11-01	Gpr139, Gpr139, gpr139, GPR139, GPR139, GNAO1
26396690	Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor. ACS Med Chem Lett Curt A Dvorak , Heather Coate , Diane Nepomuceno , Michelle Wennerholm , Chester Kuei , Brian Lord , David Woody , Pascal Bonaventure , Changlu Liu , Timothy Lovenberg , Nicholas I Carruthers	2015-09-10	-
24826842	Computer-aided discovery of aromatic l-Î±-amino acids as agonists of the orphan G protein-coupled receptor GPR139. J Chem Inf Model Vignir Isberg , Kirsten B Andersen , Christoph Bisig , Gunnar P H Dietz , Hans BrÃ¤uner-Osborne , David E Gloriam	2014-06-23	GPR139
24503482	Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors. Mol. Phylogenet. Evol. Kavita Kumari Kakarala , Kaiser Jamil	2014-05-01	GPR139
24556202	Copy number variation distribution in six monozygotic twin pairs discordant for schizophrenia. Twin Res Hum Genet Christina A Castellani , Zain Awamleh , Melkaye G Melka , Richard L O'Reilly , Shiva M Singh	2014-04-01	GPR139
23527680	Genome-wide association study of inattention and hyperactivity-impulsivity measured as quantitative traits. Twin Res Hum Genet Jane L Ebejer , David L Duffy , Julius van der Werf , Margaret J Wright , Grant Montgomery , Nathan A Gillespie , Ian B Hickie , Nicholas G Martin , Sarah E Medland	2013-04-01	CPLX2, PARD3B, GPR139, DNMT3B, DPP6, MAPRE1, CCDC192, FRMD1
19525486	Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. J Biomol Screen Liaoyuan A Hu , Pauline M Tang , Nima K Eslahi , Tian Zhou , Joseph Barbosa , Qingyun Liu	2009-08-01	GPR139
15845401	Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system. Biochem. Biophys. Res. Commun. Ayako Matsuo , Shun-ichiro Matsumoto , Mamoru Nagano , Koh-hei Masumoto , Jun Takasaki , Mitsuyuki Matsumoto , Masato Kobori , Masao Katoh , Yasufumi Shigeyoshi	2005-05-27	Gpr139, Gpr139, GPR139, GPR142
15777626	Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. Biochim. Biophys. Acta David E I Gloriam , Helgi B SchiÃ¶th , Robert Fredriksson	2005-04-15	Gpr162, Gpr139, Gpr165, Mrfap1, gpr146, gpr139, GPR146, GPR139, GPR162, GPR150, GPR148, NPSR1, GPR153, GPR152, GPR165P
12679517	The G protein-coupled receptor repertoires of human and mouse. Proc. Natl. Acad. Sci. U.S.A. Demetrios K Vassilatis , John G Hohmann , Hongkui Zeng , Fusheng Li , Jane E Ranchalis , Marty T Mortrud , Analisa Brown , Stephanie S Rodriguez , John R Weller , Abbie C Wright , John E Bergmann , George A Gaitanaris	2003-04-15	Gpr153, Gpr137, Ffar4, Lgr4, Grm2, Grm5, Grm6, Grm7, Drd1, Drd5, Gpr37l1, Ghsr, Taar2, Taar4, Gpr139, Adgrb3, Gpr142, Gpr149, Adgrb2, Hcrtr1, Gpr26, Adgrg4, Npffr1, Gpr68, Gpr150, Gpr20, Adgrg7, Gpr151, Gpr161, Tpra1, Rxfp4, Gabbr2, Adgrd1, C130060K24Rik, Mtnr1b, Gpr101, Pgr15l, Grm4, Gpr4, Gpr82, Sctr, Npsr1, Adgrl3, Gpr183, Lgr6, Adgrl1, Gpr21, Opn5, Gpr141, Gpr176, Rxfp1, Adgrf3, Lpar5, Gipr, Adgrg5, Adgrf2, Gpr62, Taar9, Adgra1, Gpr17, Gpr155, Gpr137c, Gpr173, Gpr39, Gpr22, Lpar4, Glp2r, GPR146, MRGPRE, GPR139, GPR151, ADGRG4, GPR155, ADGRF3, GPR156, ADGRG5, OPN5, ADGRF4, ADGRF5, ADGRG3, ADGRF2, ADGRF1, ADGRD1, GPR137C, GPR150, ADGRE4P, FFAR4, GPR148, GPR149, ADGRD2, GPR142, GPR141, MRGPRG, NPSR1, GPR153, GPR152, GPR135, ADGRA1

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