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12421 Rb1cc1

12421

Rb1cc1

RB1-inducible coiled-coil 1

protein-coding

Mus musculus

基因描述

Type Description
Definition RB1-inducible coiled-coil 1

研究结论

Date Results Publications
2021-01-16 15:55:00 FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function. 32580962
2020-09-19 16:28:00 Overexpression of miR-224-3p alleviates apoptosis from cerebral ischemia reperfusion injury by targeting FIP200. 31134677
2018-07-07 10:05:00 Genetic FIP200 protein deletion impairs autophagy induction and causes T cell apoptosis. 29150439
2017-09-30 13:43:00 Suggest that autophagy gene FIP200 plays a crucial role in regulating neurogenesis and restricting local immune response in postnatal neural stem cells through non-cell autonomous mechanisms. 28634261
2016-08-13 10:23:00 residues 582-585 (LQFL) in FIP200 are required for interaction with Atg13, and mutation of these residues to AAAA (designated the FIP200-4A mutant) abolished its canonical autophagy function in vitro. 27013233

名称对应

Type IDs
Synonymous 2900055E04Rik, 5930404L04Rik, Cc1, FIP200, LaXp180
Gene
UniProtKB-ID: RBCC1_MOUSE
UniprotKB: Q9ESK9
UniParc: UPI0000355FED
EMBL: AC102781, X82318, AB050017, AJ242720, AB070619, AK041038, AK159066, AC139064
Ensembl: ENSMUSG00000025907
KO: mmu:12421
Nucleutide sequences
EMBL-CDS: CAA57761.1, BAE34792.1, BAB85610.1, BAB16846.2, CAB92238.1, BAC30793.1
Ensembl_TRS: ENSMUST00000027040
Protein sequencees
Ensembl_PRO: ENSMUSP00000027040
RefSeq: XP_036012191.1, XP_011236643.1, XP_011236642.1, XP_036012227.1, XP_036012140.1, XP_006495506.1, XP_036012136.1, NP_033956.2, XP_036012163.1, XP_011236641.1, XP_011236640.1, XP_036012219.1
Others
UniRef100: UniRef100_Q9ESK9
UniRef90: UniRef90_Q9ESK9
UniRef50: UniRef50_Q8TDY2
UniGene: Mm.293811
CCDS: CCDS35507.1

全选

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研究热度

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