| Type | Description |
|---|---|
| Definition | serine (or cysteine) peptidase inhibitor, clade H, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | New specific HSP47 functions in collagen subfamily chaperoning. | 32716577 |
| 2020-09-05 13:53:00 | Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart | 31393098 |
| 2019-09-21 11:38:00 | HSP47 on the platelet surface interacts with collagen, stabilizes platelet adhesion and increases collagen-mediated signalling to mediate thrombus formation and hemostasis. | 29512284 |
| 2019-06-29 10:27:00 | Increased Hsp47 expression is associated with collagen-related disorders such as fibrosis, characterized by abnormal collagen accumulation, highlighting Hsp47's potential as a clinically relevant therapeutic target. | 30541925 |
| 2019-05-18 10:54:00 | These results highlight a cascade of fibrosis in chronic GVHD; macrophage production of transforming growth factor beta mediates fibroblast differentiation to HSP47(+) myofibroblasts that produce collagen. VA-lip HSP47 represent a novel strategy to modulate fibrosis in chronic GVHD by targeting HSP47(+) myofibroblasts without inducing immunosuppression. | 29363541 |
| Type | IDs |
|---|---|
| Synonymous | BERF-1, Cbp1, Cbp2, Hsp47, J6, Serpinh2, gp46 |
| Gene |
UniProtKB-ID:
SERPH_MOUSE
UniprotKB:
P19324
UniParc:
UPI0000003F86
EMBL:
D12907,
AK089993,
AK086523,
AK029080,
AK077937,
AK159998,
AK031457,
AC158748,
BC085143,
AK077660,
X60676,
AK090103,
AK168442,
J05609,
AK168870,
AK086519
Ensembl:
ENSMUSG00000070436
KO:
mmu:12406
|
| Nucleutide sequences |
EMBL-CDS:
BAC41093.1,
BAE40347.1,
BAC36935.1,
AAH85143.1,
CAA43091.1,
BAC39683.1,
BAA02298.1,
BAC41032.1,
BAE35546.1,
BAC26283.1,
AAA03200.1,
BAC37075.1,
BAE40689.1,
BAC39684.1,
BAC27413.1
Ensembl_TRS:
ENSMUST00000208119,
ENSMUST00000169437,
ENSMUST00000207849,
ENSMUST00000094154
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126390,
ENSMUSP00000146969,
ENSMUSP00000091706,
ENSMUSP00000147064
RefSeq:
NP_001272705.1,
NP_001104513.1,
NP_001104514.1,
XP_006507341.1,
XP_006507342.1,
NP_033955.2
|
| Others |
UniRef100:
UniRef100_P19324
UniRef90:
UniRef90_P50454
UniRef50:
UniRef50_P50454
UniGene:
Mm.22708
CCDS:
CCDS21480.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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